Dissertation:
Synthesis, Biophysical Characterization, Intramolecular and Intermolecular QSAR of Cationic-Amphiphilic Phenylpropylamines. Dr. rer. nat. Univ. Bonn, 1999

1. Klein, C.; Hopfinger, A.J. Pharmacological Activity and Membrane Interactions of Antiarrhythmics: 4D-QSAR/QSPR Analysis. Pharm. Res. 1998, 15, 303-311.
   
   
2. Klein, C.; Klingmüller, M.; Schellinski, M.; Landmann, S.; Hauschild, S.; Heber, D.; Mohr, K.; Hopfinger, A.J. Synthesis, Pharmacological and Biophysical Characterization, and Membrane-Interaction QSAR Analysis of Cationic-Amphiphilic Model Compounds. J. Med. Chem. 1999, 42, 3874-3888
   
   
3. Haidar, S.; Klein., C.; Hartmann, R.W. Synthesis and Evaluation of Steroidal Hydroxamic Acids as Inhibitors of P45017 (17α-Hydroxylase-C17-20-Lyase) Arch. Pharm. Pharm. Med. Chem. 2001, 334, 138-140
   
   
4. Klein, C.; Tabeteh, G.F.; v. Laguna, A., Holzgrabe, U.; Mohr, K. Lipophilicity and Membrane Interactions of Cationic-Amphiphilic Compounds: Syntheses and Structure-Property Relationships. Eu. J. Pharm. Sci. 2001, 14, 167-175.
   
   
5. Baston, E.; Klein, C.; Hartmann, R.W.; et al. Synthesis, evaluation, and QSAR studies of highly potent aromatase inhibitors of the piperidinedione type. Anti-Cancer Drug Design, 2001, 16, 37-47.
   
   
6. Folkers, G.; Klein, C.; Computational Methods Facilitate the Assignment of Protein Functions. Angew. Chem. Int. Ed. Engl., 2001, 40, 4175-4177.
   
   

7. Hartmann, R.W.; Ehmer, P.B.; Haidar, S.; Hector, M.; Jose, J.; Klein, C.; Seidel, S.B.; Sergejew, T.F.; Wachall, B.G.; Wächter, G.A.; Zhuang, Y. Inhibition of CYP17, a New Strategy for the Treatment of Prostate Cancer. Arch. Pharm. Pharm. Med. Chem., 2002, 4, 119-128.

8. Klein, C.,  Folkers, G. Understanding the Selectivity of Fumagillin for the Methionine Aminopeptidase Type II. Oncology Research and AntiCancer Drug Design, 2003, 13, 513-520.

9. Klein,C.; Schiffmann, R.; Folkers, G.; Piana, S.; Röthlisberger, U. Protonation States of Methionine Aminopeptidase and Their Relevance For Inhibitor Binding and Catalytic Activity. Journal of Biological Chemistry, Nov. 2003; 278: 47862 - 47867. Available online at: http://www.jbc.org/cgi/content/abstract/278/48/47862

10. Silvia De Pol, Chiara Zorn, Christian D. Klein, Oliver Zerbe, Oliver Reiser Surprisingly Stable Helical Conformations in α/β-Peptides by Incorporation of cis-β-Aminocyclopropane Carboxylic Acids. Angew. Chem. Int. Ed. 2004, 43, 511–514

11. Neugebauer, A.; Klein, C.; Hartmann, R.W. Protein-Dynamics of the Putative HCV Receptor CD81 Large Extracellular Loop. Bioorg. Med. Chem. Lett., 2004, 14, 1765-1769.

12. Klein, C. Protonation States of Methionine Aminopeptidase Studied by QM/MM Car-Parrinello Molecular Dynamics Simulations. High Performance Computing in Science and Engineering, 2003, 393-402.