We, the Institute for Virology, have an open position for one Ph.D. student (50%). The topic of the project is to evaluate the interaction of neutrophils with biomaterials and microorganisms that were designed as living therapeutic materials (LTM).
Neutrophils are predestined to function as sensors and are capable to cause an inflammatory reaction with the consequence of the LTM‘s destruction and organ damage. The aim of the project is to investigate how LTM, their ingredients and products, are capable to modulate the function of neutrophils. In general, the influence of the tumor microenvironment and microbiome on neutrophil function and on neutrophil targeting immunotherapeutic approaches in an infection-related background are in the current focus of the group. We developed novel methods to investigate neutrophil function for instance a real-time long-term impedance-based assay and organotypic 3D cultures. Both allow the illustration of complex intercellular interactions in a more physiologic environment. The respective Ph.D. student will receive a well-founded and broad training in a cell-biologic and immunologic oriented project in a dynamic and active environment with local, national, and international networks. The offer is aimed at applicants with a Master of Science/Diploma in biology, biochemistry, or similar. Preexisting experience on cell culture and immunological methods are helpful. Please send the written application by email containing a cover letter, CV, and relevant certificates and references.
Please send the written application stating the code number W1838.2 by email containing a cover letter, CV, and relevant certificates and references.
Contact: Dr Stefan Lohse (firstname.lastname@example.org)