Publications

Lyschik S, Lauer AA, Roth T, Janitschke D, Hollander M, Will T, Hartmann T, Kopito RR, Helms V, Grimm MOW, Schrul B (2022)
PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent Fashion. 
Frontiers in Cell and Developmental Biology 10, 859052. https://doi.org/10.3389/fcell.2022.859052

Puza S, Caesar S, Poojari C, Jung M, Seemann R, Hub JS, Schrul B, Fleury JB (2022)
Lipid Droplets Embedded in a Model Cell Membrane Create a Phospholipid Diffusion Barrier. 
Small 24, e2106524. https://doi.org/10.1002/smll.202106524. PMID: 35072348

Zimmermann R, Lang S, Lerner M, Förster F, Nguyen D, Helms V, Schrul B (2021)
Quantitative Proteomics and Differential Protein Abundance Analysis after the Depletion of PEX3 from Human Cells Identifies Additional Aspects of Protein Targeting to the ER.
Int J Mol Sci. 2021 Dec 1;22(23):13028. PMID: 34884833

Lauer AA, Janitschke D, Dos Santos Guilherme M., Nguyen VTT, Bachmann CM, Qiao S, Schrul B, Boehm U, Grimm HS, Hartmann T, Endres K, Grimm MOW (2021)
Shotgun lipidomics of liver and brain tissue of Alzheimer's disease model mice treated with acitretin.
Scientific Reports 2021 Jul 27;11(1):15301. PMID: 34315969

Lauer A.A., Mett J., Janitschke D., Thiel A., Stahlmann C.P., Bachmann C.M., Ritzmann F., Schrul B., Müller U.C., Stein R., Riemenschneider M., Grimm H.S., Hartmann T., Grimm M.O.W. (2020)
Regulatory feedback cycle of the insulin-degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer’s disease.
Aging Cell. 2020;19:e13264, DOI: 10.1111/acel.13264, PMID: 33128835

Dhiman R., Caesar S., Thiam AR., Schrul B. (2020)
Mechanisms of protein targeting to lipid droplets: A unified cell biological and biophysical perspective.
Semin Cell Dev Biol. 2020 Mar 20. pii: S1084-9521(18)30299-4. doi: 10.1016/j.semcdb.2020.03.004, PMID: 32201131

Exner T., Romero-Brey I., Yifrach E., Rivera-Monroy J., Schrul B., Zouboulis C.C., Stremmel W., Honsho M., Bartenschlager R., Zalckvar E., Poppelreuther M., Füllekrug J. (2019)
An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1.
J Cell Sci. 2019 Feb 11. pii: jcs.223016. doi: 10.1242/jcs.223016, PMID: 30745342

Schrul B.* and Schliebs W. (2018)
Intracellular communication between lipid droplets and peroxisomes: the Janus face of PEX19.
Biol Chem. 2018 Jun 27;399(7):741-749, PMID: 29500918
  * corresponding author

Clancy A.*, Schrul B.*, Schwappach B. (2016)
The guanine nucleotide exchange factor Gea1 rescues an isoform-specific 14-3-3 phenotype.
Matters 2016 Nov, Journal Article published 2 Nov 2016 in Matters DOI: 10.19185/matters.201609000004
  * these authors contributed equally

 Schrul B. and Kopito R.R. (2016)
Peroxin-Dependent Targeting of a Lipid Droplet-Destined Membrane Protein to ER Subdomains.
Nat Cell Biol. 2016 Jul;18(7):740-51, PMID: 27295553

 Avci D., Fuchs S., Schrul B., Fukumori A., Breker M., Frumkin I., Chen C., Biniossek M.L., Kremmer E.,
Schilling O., Steiner H., Maya Schuldiner M., Lemberg M.K. (2014)
The yeast ER-intramembrane protease Ypf1 refines nutrient sensing by regulating transporter abundance.
Mol Cell. 2014 Dec 4;56(5):630-40, PMID: 25454947

 Arakel E.C., Brandenburg S., Uchida K., Zhang H., Lin Y., Kohl T., Schrul B., Sulkin M.S., Efimov I.R.,
Nichols C.G., Lehnart S.E., Schwappach B. (2014)
Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes.
J Cell Sci. 2014 May 1;127(Pt 9):2106-19, PMID: 24569881

 Powis K.*, Schrul B.*, Tienson H, Gostimskaya I, Breker M, High S., Schuldiner M., Jakob U.,
Schwappach B. (2013)
Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane
targeting is blocked.
J Cell Sci. 2013 Jan 15;126(Pt 2):473-83, PMID: 23203805
  * these authors contributed equally

 Moreira K.E., Schuck S., Schrul B., Fröhlich F., Moseley J.B., Walther T.C., Walter P. (2012)
Seg1 Controls Eisosome Assembly and Shape
J Cell Biol. 2012 Aug 6; 198(3):405-20, PMID: 22869600

 Wolf W.*, Kilic A.*, Schrul B.*, Lorenz H., Schwappach B., Seedorf M. (2012)
Yeast Ist2 recruits the endoplasmic reticulum to specific domains of the plasma membrane.
PLoS One. 2012;7(7):e39703. Epub 2012 Jul 9, PMID: 22808051
  * these authors contributed equally

Schrul B., Kapp K., Sinning I., Dobberstein B. (2010)
Signal Peptide Peptidase (SPP) Assembles with Substrates and Misfolded Membrane Proteins into Distinct Oligomeric Complexes.
Biochem J. 2010 Apr 14;427(3):523-34. PMID: 20196774