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Direkt zu
Fakultäten
Jan-Georg Wojtyniak
Forschungsgebiete
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Lebenslauf
Seit 05/2016: Doktorand in der Klinischen Pharmazie
06/2016: Approbation zum Apotheker
11/2015 – 04/2016: Pharmazeut im Praktikum in der Landmann Apotheke, Saarbrücken
05/2015 – 10/2015: Pharmazeut im Praktikum an der Universität des Saarlandes, Saarbrücken
04/2013 - 03/2015: Studium der Pharmazie, Universität des Saarlandes, Saarbrücken
04/2011 – 03/2013: Studium der Pharmazie, Freie Universität Berlin, Berlin
07/2010 – 03/2011: Ersatzdienst beim Deutschen Roten Kreuz als Rettungssanitäter
06/2010: Abitur am Gymnasium am Rotenbühl, Saarbrücken
Publikationen
Manuskripte
Rüdesheim S, Wojtyniak JG, Selzer D, Hanke N, Mahfoud F, Schwab M, Lehr T. Physiologically based pharmacokinetic modeling of metoprolol enantiomers and α-hydroxymetoprolol to describe CYP2D6 drug-gene interactions. Pharmaceutics 2020;12(12):1200. Wojtyniak JG, Selzer D, Schwab M, Lehr T. Physiologically based precision dosing approach for drug-drug-gene interactions: a simavastatin network analysis. Clin Pharmacol Ther 2020;Epub:10.1002/cpt.2111. Wojtyniak JG, Britz H, Selzer D, Schwab M, Lehr T. Data digitizing: accurate and precise data extraction for quantitative systems pharmacology and physiologically‐based pharmacokinetic modeling. CPT Pharmacometrics Syst Pharmacol 2020;9(6):322-331. Ardelt MA, Fröhlich T, Martini E, Müller M, Kanitz V, Atzberger C, Cantonati P, Meßner M, Posselt L, Lehr T, Wojtyniak JG, Ulrich M, Arnold GJ, König L, Parazzoli D, Zahler S, Rothenfußer S, Mayr D, Gerbes A, Scita G, Vollmar AM, Pachmayr J. Inhibition of Cyclin-dependent kinase 5 - a strategy to improve sorafenib response in Hepatocellular Carcinoma Therapy. Hepatology 2019;69(1):376-393. Ramharter M, Schwab M, Mombo-Ngoma G, Zoleko Manego R, Akerey-Diop D, Basra A, Mackanga J.R, Würbel H, Wojtyniak JG, Gonzalez R, Hofmann U, Geditz M, Matsiegui P.B, Kremsner P.G, Menendez C, Kerb R, Lehr T. Population pharmacokinetics of mefloquine intermittent preventive treatment for malaria in pregnancy in Gabon. Antimicrob Agents and Chemother 2018;63(2). Schaefer N, Wojtyniak JG, Kroell AK, Koerbel C, Laschke MW, Lehr T, Menger MD, Maurer HH, Meyer MR, Schmidt PH. Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques? Biochem Pharmacol 2018;155:403-418. Miller R, Wojtyniak JG, Weckesser LJ, Alexander NC, Engert V, Lehr T. How to disentangle psychobiological stress reactivity and recovery: a comparison of model-based and non-compartmental analyses of cortisol concentrations. Psychoneuroendocrinology 2018;90:194-210. Hanke N, Teifel M, Moj D, Wojtyniak JG, Britz H, Aicher B, Sindermann H, Ammer N, Lehr T. A physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin-integration of in vitro results, Phase I and Phase II data and model application for drug-drug interaction potential analysis. Cancer Chemother Pharmacol 2018;81(2):291-304. Schaefer N, Wojtyniak JG, Kettner M, Schlote J, Laschke MW, Ewald AH, Lehr T, Menger MD, Maurer HH, Schmidt PH. Pharmacokinetics of (synthetic) cannabinoids in pigs and their relevance for clinical and forensic toxicology. Toxicol Lett 2016;253:7-16. |
Buchkapitel
| J.G. Wojtyniak, C. Dings T. Lehr. "Kardiologie" in H.G. Klein, E. Haen (Eds.): Pharmakogenetik und Therapeutisches Drug Monitoring", de Gruyter, Berlin 2018; 260-274. |
Poster
| Wojtyniak JG. A cancer cell cycle model to predict effects of combination therapy and different dosing schedules on cell cycle, tumor growth and therapy outcome. 25th Population Approach Group Europe (PAGE) meeting, 2016, Lisbon, Portugal. |
Kontakt
Jan-Georg Wojtyniak Klinische Pharmazie |