Christiane Dings

Field of research

Use of mathematical models to describe the disease development of type II diabetes mellitus and human blood coagulation

Curriculum vitae

Since 12/2015: Doctoral student Clinical Pharmacy, Saarland University, Saarbrücken and external doctoral student in the graduate research training program „PharMetrX - Pharmacometrics & Computational Disease Modelling“

12/2015: Licensed as pharmacist

05/2015 – 11/2015: Practical year und diploma, University of Iceland, Reykjavík and Saarland University, Saarbrücken

11/2014 – 04/2015: Practical year, Einhorn-Apotheke, Saarbrücken

04/2014 – 05/2015: Student/scientific assistant Clinical Pharmacy, Saarland University, Saarbrücken

01/2014 – 04/2014: Student assistant RpDoc® Solutions GmbH, Saarbrücken

10/2009 – 09/2014: Pharmacy studies, Saarland University, Saarbrücken

07/2009: Abitur, Gymnasium am Schloss, Saarbrücken

Publications

Manuscripts

Dings C, Lehr T, Vojnar B, Gaik C, Koch T, Eberhart LHJ, Huljic-Lankinen S, Murst M, Kreuer S. Population kinetic/pharmacodynamic modelling of the haemodynamic effects of cafedrine/theodrenaline (Akrinor) under general anaesthesia. Br J Clin Pharmacol. 2024. doi:10.1111/bcp.16083

Türk D, Scherer N, Selzer D, Dings C, Hanke N, Dallmann R, Schwab M, Timmins P, Nock V, Lehr T. Significant impact of time-of-day variation on metformin pharmacokinetics. Diabetologia 2023.

Dings C, Meiser P, Holzer F, Flegel M, Selzer D, Nagy E, Mösges R, Klussmann JP, Lehr T. Pharmacometric modeling of the impact of azelastine nasal spray on SARS-CoV-2 viral load and related symptoms in COVID-19 patients. Pharmaceutics 2022;14(10):2059.

Dings C, Götz KM, Och K, Sihinevich I, Werthner Q, Smola S, Bliem M, Mahfoud F, Volk T, Kreuer S, Rissland J, Selzer D, Lehr T. Model-based analysis of SARS-CoV-2 infections, hospitalization and outcome in Germany, the federal states and districts. Viruses 2022;14(10):2114.

Scherer N, Kurbasic A, Dings C, Mari A, Nock V, Hennige AM, Koivula RW, Laakso M, Siloaho M, McDonald TJ, Pavo I, Giordano GN, Hansen TH, Rutters F, Dekker JM, Jablonka B, Ruetten H, Pearson ER, Franks PW, Lehr T. The impact and correction of analysis delay and variability in storage temperature on the assessment of HbA1c from dried blood spots - an IMI DIRECT Study. Int J Proteom Bioinform 2019;4(1):7-13.

Scherer N, Dings C, Böhm M, Laufs U, Lehr T. Alternative treatment regimens with the PCSK9 inhibitors alirocumab and evolocumab: a pharmacokinetic and pharmacodynamic modeling approach. J Clin Pharmacol 2017;57(7):846-54.

Posters

Dings C, Scherer N, Freijer J, Nock V, Lehr T. Mathematical modeling of glucose, insulin and c-peptide during the OGTT in pre-diabetic subjects: a DIRECT study. 26th Population Approach Group Europe (PAGE) meeting, 2017, Budapest, Hungary.

Dings C, Lehr T. Pharmacokinetic/pharmacodynamic modeling of acetylsalicylic acid and its major metabolite salicylic acid. 25th Population Approach Group Europe (PAGE) meeting, 2016, Lisbon, Portugal.

Dings C, Schäftlein A, Lehr T. Predicting the impact of oral anticoagulants on the human coagulation pathway using a comprehensive systems pharmacology model. Annual meeting of the German Pharmaceutical Society (DPhG), 2014, Frankfurt (Main), Germany.