Publications

Makhro, A., Huisjes, R., Seiler, E., Qiao, M., Bartels, M., Hegemann, I., Eppenberger, P., Bender, N., Dorn, I., Bogdanova, A., van Wijk, R., Kaestner, L. (2026) Mechanistic consequences of Piezo1 gain-of-function variants for decreased red cell survival in Hereditary Xerocytosis. Am. J. Hem., 101, 619-622. doi: 10.1002/ajh.70188.

Asghariastanehei, B., Martin, M., Nader, E., Rezigue, H., de Wreede, A., Dargaud, Y., Nougier, C., Joly, P., Niñoé, A., Egée, S., Kaestner, L., Connes, P. (2026) Red blood cell Piezo1 Activation Drives Faster Coagulation and Structural Alterations in Blood Clots through Red Blood Cell Deformability Impairment. Sem. Thromb. Hemost., 52, 601-612. doi: 10.1055/a-2846-3643.

Penttinen, R., Coli, A., Hintermaier, F., Murciano, N., Holzhauser, S., Gao, S., Rotordam, M.G., George, M., Fertig, N., Kaestner, L. (2025) Optogenetics meets automated patch clamp. iScience, 29, 116709.

Rashidi, Y., Maurer, F., Wrublewsky, S., Larhrissi, K., John, T., Fidley, F., Toye, A., Kaestner, L., Wagner, C., Laschke, M.W., Darras, A. (2026) Impact of Red Blood Cell Rigidity on in vivo Flow Dynamics and Lingering in Bifurcations. Biophys. J., 125, 1904-1913. doi: 10.1016/j.bpj.2026.03.023.

Hernandez, C.A., Traets, M.J.M, van Solinge, W.W., Rijneveld, A.W., Kaestner, L., John, T., Nur, E., Biemond, B.J., Kuypers, F.A., van Beers, E.J., Rab, M.A.E., van Wijk, R. (2026) Oxidantscan: A novel biomarker to assess red blood cell susceptibility to oxidative stress in sickle cell disease. Blood Cells, Molecules and Diseases  117, 102967.

Caputo, A., Kaestner, L., Quint, S. (2026). A Novel Semi-Supervised Approach for Red Blood Cell Shape Analysis in Flow. In: S. Bakas, G. Zamzmi, & X. Li (eds.), Medical Image Computing and Computer Assisted Intervention. Cham, Switzerland: Springer Nature Switzerland AG.

Vacca, F., Yalcin, B., Kaestner, L., Danek, A., Peikert, K., Walker, R.H., Muhammad, A. (2026) Proceedings of the 12th International Meeting on Neuroacanthocytosis, Cohen Syndrome, and Other VPS13-Related Disorders. Tremor and other hyperkinetic movements. 16, 1–23.

Kaestner, L., Egee, S., Connes, P., Bogdanova, A., Simmonds, M. (2025) Splenic Filtration of Red Blood Cells: Physics, Chemistry, and Biology need to go hand in hand. PNAS,122: e2405086121.doi: 10.1073/pnas.2405086121.

Maurer, F., Romero, C., Lerch, N., John, T., Kaestner, L., Wagner, C., Darras, A. (2025) Band pattern formation of erythrocytes in density gradients is due to competing aggregation and net buoyancy. PNAS, 122(519), e2515704122.

Minetti, G., Dorn, I., Köfeler, H., Perotti, C., Kaestner, L (2025) Insights from lipidomics into the terminal maturation of circulating human reticulocytes. Cell Death Discovery, 11, 79.

Kuck, L., Kaestner, L., Egée, S., Lew, V.L., Simmonds, M.J. (2025) Mechanotransduction mechanisms in human erythrocytes: Fundamental physiology and clinical significance, CHANNELS, 19(1), 2556105.

Bernhardt, I., Kaestner, L. (2025) Historical view and some unsolved problems in red blood cell membrane research. Frontiers in Bioscience - Landmark, 30: 25331.

Qiao, M., Penttinen, R.,Coli, A., Murciano, N., Maurer, F.M., Wagner, C., Rotordam, M.G., Kaestner, L. (2025) Piezo1 Channel Activators Yoda1 and Yoda2 in the Context of Red Blood Cells. Biomolecules, 15(8), 1110.

John, T., Kretsch, K., Maurer, F.M., Recktenwald, S.M., Kaestner, L., Wagner, C. (2025) Viscosity and density measurements on the cytosol of human red blood cells. Biophys. J., 124(16), 2668-2676.

Cloos, A.-S., Ghodsi, M., Stommen, A., Steffen M. Recktenwald, S.M., Kaestner, L., Danek, A., Spranger, A., Hermann, A., Peikert, K., Tyteca, D.(2025) Red blood cell lipid distribution in the pathophysiology and laboratory evaluation of chorea-acanthocytosis and McLeod syndrome patients. Front. Physiol., 16, 1543812.

Sardari, V., Mohammadian, M., Asfia, S., Maurer, F., Örüm, D., Seemann, R., John, T., Kaestner, L., Wagner, C., Maleki, M., Darras, A. (2025) Deposit of Red Blood Cells at low concentrations in evaporating droplets is dominated by a central edge growth, J. Colloid Interface Sci., 679(A), 939-946.

Hemmer, S., Hui, X., Draeger, J., Menges, J., Schwarz, E.C., Wrede, A., Oertel, J., Kaestner, L., Jung, G., Urbschat, S. (2025) A novel fluorescent diagnostic probe as a potential Point-of-Care diagnostic tool to estimate recurrence risk of meningiomas. Surgical Reviews, 48, 27.

Kaestner, L., Schlenke, P., von Lindern, M., El Nemer, W. (2024) Translatable tool to quantitatively assess the quality of red blood cell units and tailored cultured red blood cells for transfusion. PNAS, 121: e2318762121.

Stauffer, E., Pichon, A., Champigneulle, B., Furian, M., Hancco, I., Darras, A., Robach, P., Brugniaux, J.V., Nader, E., Connes, P., Verges, S., Kaestner, L. (2024) Making a virtue out of an evil: Are red blood cells from chronic mountain sickness patients eligible for transfusions? Am J. Hem., 99, 1407-1410. doi: 10.1002/ajh.27317

D’Alessandro, A., Earley, E., Nemkov, T., Stephenson, D., Dzieciatkowska, M., Hansen, K., Minetti, G., Champigneulle, B., Stauffer, E., Pichon, A., Furian, M., Verges, S., Kleinman, S., Norris, P.J., Busch, M.P., Page, G.P., Kaestner, L. (2024) Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude, PNAS, 121(1), e2315930120.

Earley, E.J., D’Alessandro, A., Kaestner, L., Page, G.P. (2024) Reply to "An intronic polymorphism associated with 2,3-BPG levels in human erythrocytes is linked to expression of RhCE blood groups”. PNAS, 121: e2413726121.

Coli, A., Gao, S., Kaestner, L. (2024) Sodium-Selective Channelrhodopsins. Cells,13: 1852.

Hernández, C.A. Kevin Peikert, K., Min Qiao, M., Darras, A., de Wilde, J.R.A., Bos, J., Leibowitz, M., Galea, I., Wagner, C., Rab, M.A.E., Walker, R.H., Hermann, A., van Beers, E.J., van Wijk, R., Kaestner, L. (2024) Osmotic Gradient Ektacytometry – A Novel Diagnostic Approach for Neuroacanthocytosis Syndromes, Front. Neurosci., 18, 1406969. doi: 10.3389/fnins.2024.1406969

Champigneulle, B., Caton, F., Seyve, L., Stauffer, E., Pichon, A., Brugniaux, V.J., Furian, M., Hancco, I., Deschamps, B., Kaestner, L., Robach, P., Connes, P. Bouzat, P., Polack, B., Marlu, R., Verges, S. (2024) Are coagulation profiles in Andean highlanders with excessive erythrocytosis favouring hypercoagulability?, Exp. Physiol., 109, 899-914. doi: 10.1113/EP091670.

Petkova-Kirova, P., Murciano, N., Iacono, G., Jansen, J., Simionato, G., Qiao, M., van der Zwaan, C., Rotordam, G.M., John, T., Hertz, L., Hoogendijk, A.J., Becker, N., Wagner, C., von Lindern, M., Egee, S., van den Akker, E., Lars Kaestner, L. (2024) The Gárdos channel and Piezo1 revisited: Comparison between reticulocytes and mature red blood cells. IJMS, 25: 1416.

John, T., Kaestner, L., Wagner, C., Darras, A. (2024) Early stage of Erythrocyte Sedimentation Rate test: Fracture of a high-volume-fraction gel. PNAS Nexus,3: pgad416. doi: 10.1093/pnasnexus/pgad416

Murciano, N., Kaestner, L. (2024) The putative role of the Transient Receptor Potential ion channel of Vanilloid type 2 (TRPV2) in red blood cell storage lesions. Transfusion Medicine and Hemotherapy, 51, 52-54. doi: 10.1159/000531282.

Hatem, A., Esperti, S., Murciano, N., Quia, M., Rotordam, M.G., Becker, N., Nader, E., Maurer, F., Peres, L., Bouyer, G., Kaestner, L., Connes, P., Egee, S. (2023) Adverse effects of delta-9-tetrahydrocannabinol on sickle red blood cells. Am J. Hem.  98: E383-E386.

van Dijk, M.J., van Oirschot, B.A., Harrison, A.N., Recktenwald, S.M., Qiao, M., Stommen, A., Cloos, A.-S., Vanderroost J., Terrasi, R., Dey, K., Bos, J., Rab, M.A.E., Bagdanova, A., Minetti, G., Muccioli, G.G., Tyteca, D., Egee, S., Kaestner, L., Molday, R.S., van Beers, E.J., van Wijk, R. (2023) A novel missense variant in ATP11C is associated with reduced red blood cell phosphatidylserine flippase activity and mild hereditary hemolytic anemia. Am J. Hem.  98: 1877-1887.

Murciano , N., Rotordam M.G., Becker N., Parsonage G., Ludlow M.J., Darras, A., Kaestner, L., Beech, D.J., George, M., Fertig, N., Brüggemann, A. (2023) A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation. J. Gen. Physiol., 155: e202213132. doi: 10.1085/jgp.202213132

Kaestner, L., Champigneulle, B., Stauffer, E., Furian, M., De Abreu, J. John, T., Nader, E., Scheller, A., Pichon, A., Connes, P., Robach, P., Brugniaux, J.V., Borsch, C., Rudloff, S., Mairbäurl, Verges, S. (2023) Neocytolysis after return from high altitude (5100 m): Further evidence for absentia. Acta Physiol.,128: e14002.

Lopes, M.G.M., Recktenwald, S.,M., Simionato, G., Eichler, H., Wagner, C., Quint, S., Kaestner, L. (2023) Big data in transfusion medicine and artificial intelligence analysis for red blood cell quality control. Transfusion Medicine and Hemotherapy  50, 163–173, doi: 10.1159/000530458.

Nouaman, M., Darras, A., John, T., Simionato, G., Rab, M.A.E., van Wijk, R., Laschke, M.W., Kaestner, L., Wagner, C., Recktenwald, S.M. (2023) Effect of red blood cell age and membrane rigidity on microcapillary flow. Cells, 12: 1529.

Hertz, L., Flormann, D., Birnbaumer, L., Wagner, C., Laschke, M.W., Kaestner, L.(2023) Evidence of in vivo exogen protein uptake by red blood cells -a putative therapeutic concept. Blood Adv. 7, 1133-1139.

Rashidi, Y., Simionato, G., Zhou, Q., John, T., Kihm, A., Bendaoud, M., Krüger, T., Bernabeu, M.O., Kaestner, L., Laschke, M.W., Menger, M.D., Wagner, C., Darras, A.. (2023) Red blood cell lingering modulates hematocrit distribution in the microcirculation. Biophys. J., 122, 1526–1537.

Darras, A., John, T., Wagner, C., Kaestner, L.(2023) Erythrocyte Sedimentation Rate: A Physics-Driven Characterization in Medical Context. J. Vis. Exp., 24(193): doi: 10.3791/64502.

Bianchi, P., Makhro, A., Egee, S., Kaestner L. (2023) Blood group meets ion channel - an unexpected marriage, Blood, 141(2): 146.

Flormann, D., Qiao, M., Murciano, N., Iacono, G., Darras, A., Hof, S., Recktenwald, S.M., Rotordam, M.G., Becker, N., Geisel, J., Wagner, C., von Lindern, M., van den Akker, E., Kaestner, L. (2022) Transient Receptor Potential channel Vanilloid type 2 in red cells of cannabis consumer. Am. J. Hematol. 97, E180-E183, doi: 10.1002/ajh.26509.

Minetti, G, Bogdanova, A, Maierbäurl, H., Kaestner, L. (2022) Space anemia unexplained: red blood cells seem to be space-proof. Am. J. Hematol., 97(10), E365-E367.doi.org/10.1002/ajh.26663.

Kaestner, L. (2022) Artificial intelligence: Training the trainer. Br. J. Haematol., 198, 805-806. DOI: 10.1111/bjh.18358.

Fenk, S., Melnikova, E.V., Anashkina, A.A., Poluektov, Y.M., Zaripov, P.I., Mitkevich, V.A., Tkachev, Kaestner, L., Minetti, G., Mairbäurl, H., Goede, J.S., Makarov, A.A., Petrushanko, I.Y., Bogdanova, A. (2022) Hemoglobin is an oxygen-dependent glutathione buffer adapting the intracellular reduced glutathione levels to oxygen availability. Redox Biology, 58: 102535.

Recktenwald, S.M., Simionato, G., Lopes, M.G.M., Gamboni, F., Dzieciatkowska, M., Meybohm, P., Zacharowski, K., von Knethen, A., Wagner, C., Kaestner, L., D’Alessandro, A., Quint, S. (2022) Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19. eLife, 11: e81316.

Maurer, F., John, T., Makhro, A., Bogdanova, A., Minetti, G., Wagner, C., Kaestner, L. (2022) Continuous Percoll Gradient Centrifugation of Erythrocytes-Explanation of Cellular Bands and Compromised Age Separation. Cells, 11, 1296. /doi.org/ 10.3390/cells11081296

Recktenwald, S.M., Lopes, M.G.M., Peter, S., Hof, S., Simionato, G., Peikert, K., Hermann, A., Danek, A., van Bentum, K., Eichler, H., Wagner, C., Quint, S., Kaestner, L. (2022) Erysense, a lab-on-a-chip-based point-of-care device, to evaluate red blood cell flow properties with multiple clinical applications. Front. Physiol., 13, 1884690.

Darras, A., Dasanna, A.K., John, T., Gompper, G., Kaestner, L., Fedosov, D.A., Wagner, C. (2022) Erythrocyte sedimentation: Fracture and collapse of a high-volume-fraction soft-colloid gel. Phys. Rev. Lett.,128,088101, DOI: 10.1103/PhysRevLett.128.088101.

Reichel, F., Kräter, M., Peikert, K., Glaß, H., Rosendahl, P., Herbig, M., Rivera Prieto, A., Kihm, A., Bosman, G., Kaestner, L., Hermann, A., Guck J. (2022) Changes in blood cell deformability in Chorea-Acanthocytosis and effects of treatment with dasatinib or lithium. Front. Physiol., 13, 852946. doi: 10.3389/fphys.2022.852946.

Simionato, G., Rabe, A., Gallego-Murillo, J.S., van der Zwaan, C., Hoogendijk, A.J., van den Biggelaar, M., Minetti, G., Bogdanova, A., Mairbäurl, H., Wagner, C., Kaestner, L., van den Akker, E. (2022) In vitro erythropoiesis at different pO₂ induces adaptations that are independent of prior systemic exposure to hypoxia. Cells, 11, 1082. doi.org/10.3390/cells11071082.

Jansen, J., Qiao, M., Hertz, L., Wang, X., Fermo, E., Zaninoni, A., Colombatti, R., Bernhardt, I., Bianchi, P., Kaestner, L. (2021) Mechanistic ion channel interactions in red cells of patients with Gárdos channelopathy. Blood Advances, 5, 3303-3308. doi.org/10.1182/bloodadvances.2020003823

Klein, M., Kaestner, L., Bogdanova, A.Y., Minetti, G., Rudloff S., Lundby, C., Makhro, A., Seiler, E., van Cromvoirt, A., Fenk, S., Simionato, G., Hertz, L., Recktenwald, Schäfer, L., Haider, T., Fried, S., Borsch, Marti, H.H., Sander, A., Mairbäurl, H. (2021) Absence of neocytolysis in humans returning from a three-week high-altitude sojourn. Acta Physiol., 232(3):e13647. doi: 10.1111/apha.13647

Rabe, A., Kihm, A., Darras, A., Peikert, K., Simionato, G., Dasanna, A.K., Glaß, H., Geisel, J., Quint, S., Danek, A., Wagner, C., Fedosov, D.A., Hermann, A., Kaestner, L. (2021) The Erythrocyte Sedimentation Rate and Its Relation to Cell Shape and Rigidity of Red Blood Cells from Chorea-Acanthocytosis Patients in an Off-Label Treatment with Dasatinib. Biomolecules, 11, 727; doi: 10.3390/biom11050727

Darras, A., Peikert, K., Rabe, A., Yaya, F., Simionato, G., John, T., Kumar Dasanna, A., Buvalyy, S., Geisel, J., Hermann, A., Fedosov, D.A., Danek, A., Wagner, C., Kaestner, L. (2021) Acanthocyte sedimentation rate as a diagnostic biomarker for neuroacanthocytosis syndromes: experimental evidence and physical justification. Cells, 10, 788; doi: 10.3390/cells10040788.

Simionato, G., Hinkelmann, K., Chachanidze, R., Bianchi, P., Fermo, E., Wijk, R. van, Leonetti, M., Wagner, C., Kaestner, L. Quint, S. (2021). Red blood cell phenotyping from 3D confocal images using artificial neural networks. PloS Comp. Biol., 17, e1008934. doi: org/ 10.1371/journal.pcbi.1008934.

Wang, J., Hertz, L., Ruppenthal, S., El Nemer, W., Connes, P., Goede, J.S., Bogdanova, A., Birnbaumer, L., Kaestner, L. (2021) Lysophosphatidic acid activated calcium signaling is elevated in red cells from sickle cell disease patients. Cells, 10, 456.

Kaestner, L., Laschke, M.W., John, T., Wagner, C., Bogdanova, A. (2021) Do fluorocarbons substantially increase transdermal oxygen delivery? A proof-of-principle study in mice. Open Research Europe, 1, 39.

Martin-Wortham, J., Recktenwald, S., Lopes, M., Kaestner, L., Wagner, C., Quint, S. (2021) A deep learning-based concept for high throughput image flow cytometry. Appl. Phys. Lett., 118, 123701.

Kihm, A., Quint, S., Laschke, M.W., Menger, M.D., John, T., Kaestner, L., Wagner, C. (2021) Lingering Dynamics in Microvascular Blood Flow. Biophys. J., 120, 432-439.

Aglialoro , F., Abay, A., Yagci, N., Rab, M.A.E., Kaestner, L., van Wijk, R., von Lindern, M., van den Akker, E. (2021) Mechanical stress induces Ca²⁺ dependent signal transduction in erythroblasts and modulates erythropoiesis. IJMS, 22, 955.

Fermo, E., Monedero Alonso, D., Petkova-Kirova, P., Makhro, A., Pérès, L., Bouyer, G., Marcello, A.P., Longo, F., Graziadei, G., Barcellini, W., Bogdanova. A., Egee, S., Kaestner, L., Bianchi, P. (2020) Gardos channelopathy: functional analysis of a novel KCNN4 variant. Blood Advances, 4, 6336-6341.

Kaestner, L., Bogdanova, A. and Egee, S. (2020). Calcium channels and calcium-regulated channels in human red blood cells. Adv. Exp. Med. Biol., 1131, 625-648. doi: 10.1007/978-3-030-12457-1_25.

Abay, A., Recktenwald, S.M., John, T., Kaestner, L., Wagner, C. (2020) Cross-sectional focusing of red blood cells in a constricted microfluidic channel, Soft Matter, 16, 534-543.

Ermolinskiy, P., Lugovtsov, A., Yaya, F., Lee, K., Kaestner, L., Wagner, C., Priezzhev, A. (2020), Effect of Red Blood Cell Aging In Vivo on Their Aggregation Properties In Vitro: Measurements with Laser Tweezers. Applied Sciences, 10, 7581.

Bissinger, R., Petkova-Kirova, P., Mykhailova, O., Oldenborg, P.-A., Novikova, E., Donkor, D.A., Dietz, T., Al Mamun Bhuyan, A., Sheffield, W.P., Grau, M., Artunc, F., Kaestner, L., Acker, J.P., Qadrie S.M. (2020) Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells, Cell. Commun. Signal., 18, 155.

Huisjes, R., Makhro, A., Llaudet-Planas, E., Hertz, L., Petkova-Kirova, P., Verhagen, L.P., Pignatelli, S., Rab, M.A.E., Schiffelers, R.M., Seiler, E., van Solinge, W.W., Vives Corrons, J.L., Mañú-Pereira, M., Kaestner, L., Bogdanova, A., van Wijk, R. (2020) Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis, Haematologica, 105(2): 338-347.

Makhro, A., Hegemann, I., Seiler, E., Simionato, G., Claveria, V., Bogdanov, N., Sasselli, C., Torgeson, P., Kaestner, L., Manz, M., Goede, J., Gassmann, M., Bogdanova, A. (2020) A pilot clinical phase II trial MemSID: Acute and durable changes of red blood cells of sickle cell disease patients on memantine treatment. eJHeam,.10.1002/jha2.11.

Kaestner, L., Bianchi, P. (2020) Trends in the development of diagnostic tools for red blood cell related diseases and anaemias, Front. Physiol.  11, 387.

Kaestner, L. (2020) Artificial Intelligence Meets Hematology, Trans. Aph. Sci.  59 (6), 102986.

Bogdanova, A., Kaestner, L., Simionato, G., Wickrema, A., Makhro, A. (2020) Heterogeneity of red blood cells: causes and consequences, Front. Physiol.  11: 392.

Rotordam, G.M., Fermo, E., Becker, N., Barcellini, W., Brüggemann, A., Fertig, N., Egée, S., Markus Rapedius, M., Bianchi, P., Kaestner, L. (2019) A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp. Haematologica, 104, e181.

Pretini, V., Koenen, M.H., Kaestner, L., Fens, M.H.A.M., Schiffelers, R.M., Bartels, M., Van Wijk, R. (2019) Red Blood Cells: Chasing Interactions, Front. Physiol., 10, 945.

Abay, A., Simionato, G., Chachanidze, R., Bogdanova, A., Hertz, L., Bianchi, P., van den Akker, E., von Lindern, M., Leonetti, M., Minetti, G., Wagner, C., Kaestner, L. (2019) Glutaraldehyde – a subtle tool in the investigation of healthy and pathologic red blood cells, Frontiers in Physiology, 10, 514.

Bernhardt, I., Wesseling, M.C., Nguyen, D.B., Kaestner, L. (2019) Red blood cells actively contribute to blood coagulation and thrombus formation. In: A. Tombak (ed.) Erythrocyte, London: IntechOpen, DOI: dx.doi.org/10.5772/intechopen.86152

Hertz, L., Ruppenthal, S., Simionato, G., Quint, S., Kihm, A., Abay, A., Petkova-Kirova, P., Boehm, U., Weissgerber, P., Wagner, C., Laschke, M.W., Kaestner, L. (2019) The evolution of erythrocytes becoming red in respect to fluorescence, Frontiers in Physiology, 10, 753. doi: 10.3389/fphys.2019.00753.

Liu, Z., Zhang, P., Kaestner, L., Volmer, D.A. (2019) A simple MALDI target plate with channel design to improve detection sensitivity and reproducibility for quantitative analysis of biomolecules, J. Mass Spectrometry,  54, 878-884.

Tian, Q., Schröder, L., Schwarz, Y., Flockerzi, A., Kaestner, L., Zeug, A., Bruns, D., Lipp, P. (2019) Large scale, unbiased analysis of elementary calcium signaling events in cardiac myocytes, JMCC, 135, 79-89.

Kaiser, E., Tian, Q., Wagner, M., Barth, M., Xian, W., Schroeder, L.,  Ruppenthal, S.,  Kaestner, L., Boehm, U., Wartenberg, P., Lu, H., McMillin, S.M., Bone, D.B., Wess, J., Lipp, P. (2019) DREADD technology reveals major impact of Gq signaling on cardiac electrophysiology. Cardiovasc. Res., cvy251.

Bruggemann, A., Rotordam, G.M., Becker, N., Fertig, N., Bianchi, P., Rapedius, M., Kaestner, L. (2019) A Novel Gain of Function Mutation of Piezo-1 is Investigated in Red Blood Cells by High-Throughput Patch Clamp. Biophys. J. 116, 244a-245a.

Petkova-Kirova, P., Hertz, L., Danielczok, J., Huisjes, R., Makhro, A., Bogdanova, A., del Mar Mañú-Pereira, M., Vives Corrons, J.L., van Wijk, R. Kaestner, L. (2019) Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias, Frontiers in Physiology, 10, 386.

Huisjes, R., Bogdanova, A., van Solinge, W.W., Schiffelers, R.M., Kaestner, L., van Wijk, R. (2018) Squeezing for life – properties of red blood cell deformability Front. Physiol. 9, 656.

Petkova-Kirova, P., Laura Hertz, L., Makhro, A., Danielczok, J., Huisjes, R., Llaudet-Planas, E., Mañu-Pereira, M.M. Vives Corrons, J.-L., van Wijk, R., Bogdanova, A., Kaestner, L. (2018) A previously unrecognized Ca²⁺-inhibited non-selective cation channel in red blood cells. HemaSphere, 2, e146.

Kihm, A., Kaestner, L., Wagner, C., Quint, S. (2018) Classification of red blood cell shapes in flow using outlier tolerant machine learning. PLoS Comput. Biol., 14, e1006278.

Bächer, C., Kihm, A., Schrack, L., Kaestner, L., Laschke, M., Wagner, C., Gekle, S.(2018) Anti-margination of microparticles and platelets in the vicinity of branching vessels. Biophys. J., 115, 411-425.

Kaestner, L., Bogdanova, A. (2018) Editorial: The red cell life-cycle from erythropoiesis to clearance Front. Physiol. 9, 1537.

Kaestner, L., Wang, X., Hertz, L., Bernhardt, I. (2018) Voltage-activated ion channels in non-excitable cells - a viewpoint regarding their physiological justification Front. Physiol. 9, 450.

Bogdanova, A., Kaestner, L. (2018) The Red Blood Cells on the move! Front. Physiol. 9, 474.

Bogdanova, A., Kaestner, L., Minetti, G (2018) Neocytolysis: When young red blood cells die first, Open Access Government - Research & Innovation News, www.openaccessgovernment.org/neocytolysis-red-blood-cells/53026/

Kaestner, L., Zeug, A., Tian, Q. (2018) Optogenetic tools in the microscopy of cardiac excitation-contraction coupling. In: L. Kaestner, P. Lipp (eds.) Microscopy of the Heart, Berlin, Heidelberg, New York: Springer, 97-117.

Flügel, K., Tian, Q., Kaestner, L. (2018) Optical sectioning microscopy at ‘temporal super-resolution’. In: L. Kaestner, P. Lipp (eds.) Microscopy of the Heart, Berlin, Heidelberg, New York: Springer, 21-35.

Kaestner, L., Minetti, G. (2017) The potential of erythrocytes as cellular aging models. Cell Death Diff.  24, 1475–1477.

Danielczok, J.G., Terriac, E., Hertz, L., Petkova-Kirova, P., Lautenschläger, F., Laschke, M.W., Kaestner, L. (2017) Red blood cell passage of small capillaries is associated with transient Ca²⁺-mediated adaptations. Frontiers in Physiology, 8, 979.

Tian, Q., Kaestner, L., Schröder, L., Guo, J., Lipp, P. (2017) An adaptation of astronomical image processing enables characterization and functional 3D mapping of individual sites of excitation-contraction coupling in rat cardiac muscle. eLife, 6:e30425.

Hertz, L., Huisjes, R., Llaudet-Planas, E., Petkova-Kirova, P., Makhro, A., Danielczok, J., Egee, S., Mañú-Pereira, M.M., van Wijk, R., Vives Corrons, J.-L., Bogdanova, A., Kaestner, L. (2017) Is Increased Intracellular Calcium in Red Blood Cells a Common Component in the Molecular Mechanism Causing Anemia? Frontiers in Physiology,  8, 673.

Quint, S., Christ, A. F., Guckenberger, A., Himbert, S., Kaestner, L., Gekle S., Wagner, C. (2017) 3D tomography of cells in micro-channels, Appl. Phys. Lett., 111,103701.

Flormann, D., Aouane, O., Kaestner, L., Ruloff, C., Misbah, C., Podgorski, T., Wagner, C. (2017) The buckling instability of aggregating red blood cells. Scientific Reports, 7, 7928.

Fermo, E., Bogdanova, A.Y.,Petkova-Kirova, P., Zaninoni, A., Marcello, A. P., Makhro, A., Haenggi, P., Hertz, L., Danielczok, J., Vercellati C., Mirra, N., Zanella, A., Cortelezzi, A., Barcellini, W., Kaestner, L., Bianchi, P. (2017) ‘Gardos Channelopathy’: a variant of hereditary Stomatocytosis with complex molecular regulation, Scientific Reports, 7: 1744.

Danielczok, J., Hertz, L., Ruppenthal, S., Kaiser, E., Petkova-Kirova, P., Bogdanova, A., Krause, E., Lipp, P., Freichel, M., Birnbaumer, L., Kaestner, L. (2017) Does Erythropoietin regulate TRPC channels in red blood cells? Cell. Physiol. Biochem., 41, 1219-1228. 

Hui, X., Sauer, B., Kaestner, L., Kruse, K., Lipp, P. (2017) PKCα diffusion and translocation are independent of an intact cytoskeleton, Scientific Reports, 7: 475.

Himbert, S., Alsop, R., Rose, M., Hertz, L., Dhaliwal, A., Moran-Mirabal, J.; Verschoor, C., Bowdish, D., Kaestner, L., Wagner, C., Rheinstadter, M. (2017) The Molecular Structure of Human Red Blood Cell Membranes from Highly Oriented, Solid Supported Multi-Lamellar Membranes, Scientific Reports, 7, 39661.