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- Fatemi N, Mirbahari SN, Tierling S, Sanjabi F, Shahrivari S, AmeliMojarad M, Amelimojarad M, Mirzaei Rezaei M, Nobaveh P, Totonchi M, Nazemalhosseini Mojarad E.
Emerging Frontiers in Colorectal Cancer Therapy: From Targeted Molecules to Immunomodulatory Breakthroughs and Cell-Based Approaches.
Dig Dis Sci, 2025, Jan 27.doi: 10.1007/s10620-024-08774-2.
- Schaffner SL, Casazza W, Artaud F, Konwar C, Merrill SM, Domenighetti C, Schulze-Hentrich JM, Lesage S, Brice A, Corvol JC, Mostafavi S, Dennis JK, Elbaz A, Kobor MS; DIGPD Study Group.
Genetic variation and pesticide exposure influence blood DNA methylation signatures in females with early-stage Parkinson's disease.
NPJ Parkinsons Dis, 2024, 10(1):98.doi: 10.1038/s41531-024-00704-3.
- Schaffner SL, Wassouf Z, Hentrich T, Nuesch-Germano M, Kobor MS, Schulze-Hentrich JM.
Distinct impacts of alpha-synuclein overexpression on the hippocampal epigenome of mice in standard and enriched environments.
Neurobiol Dis, 2023, 186:106274.doi: 10.1016/j.nbd.2023.106274. - Yaldiz B, Kucuk E, Hampstead J, Hofste T, Pfundt R, Corominas Galbany J, Rinne T, Yntema HG, Hoischen A, Nelen M, Gilissen C; Solve-RD consortium.
Twist exome capture allows for lower average sequence coverage in clinical exome sequencing.
Hum Genomics, 2023, 17(1):39.doi: 10.1186/s40246-023-00485-5. - Fitzel R, Secker-Grob KA, Keppeler H, Korkmaz F, Schairer R, Erkner E, Schneidawind D, Lengerke C, Hentrich T, Schulze-Hentrich JM, Schneidawind C.
Targeting MYC in combination with epigenetic regulators induces synergistic anti-leukemic effects in MLLr leukemia and simultaneously improves immunity.
Neoplasia, 2023, 41:100902.doi: 10.1016/j.neo.2023.100902. - Edelmann S, Wiegand A, Hentrich T, Pasche S, Schulze-Hentrich JM, Munk MHJ, Fallgatter AJ, Kreifelts B, Nieratschker V.
Blood transcriptome analysis suggests an indirect molecular association of early life adversities and adult social anxiety disorder by immune-related signal transduction.
Front Psychiatry, 2023, 14:1125553.doi: 10.3389/fpsyt.2023.1125553. - Kilzheimer A, Hentrich T, Rotermund C, Kahle PJ, Schulze-Hentrich JM.
Failure of diet-induced transcriptional adaptations in alpha-synuclein transgenic mice.
Hum Mol Genet, 2023, 13;32(3):450-461. doi.org/10.1093/hmg/ddac205. - Xylaki M, Paiva I, Al-Azzani M, Gerhardt E, Jain G, Islam MR, Vasili E, Wassouf Z, Schulze-Hentrich JM, Fischer A, Outeiro TF.
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy.
J Parkinsons Dis, 2023, 13(2):179-196. doi.org/10.3233/JPD-225055.
Buchert R, Schenk E, Hentrich T, Weber N, Rall K, Sturm M, Kohlbacher O, Koch A, Riess O, Brucker SY, Schulze-Hentrich JM.
Genome Sequencing and Transcriptome Profiling in Twins Discordant for Mayer-Rokitansky-Küster-Hauser Syndrome.
J Clin Med, 2022, 23;11(19):5598.doi: 10.3390/jcm11195598.Schaffner SL, Wassouf Z, Lazaro D, Xylaki M, Gladish N, Lin DTS, MacIsaac J, Ramadori K, Schulze-Hentrich JM, Outeiro TF, Kobor MS.
Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways.
Hum Mol Genet, 2022, 31(21):3694-3714. doi.org/10.1093/hmg/ddac104.Haas E, Incebacak RD, Hentrich T, Maringer Y, Schmidt T, Zimmermann F, Casadei N, Mills JD, Aronica E, Riess O, Schulze-Hentrich JM, Hübener-Schmid J.
A novel SCA3 knock-in mouse model mimics the human SCA3 disease phenotype including neuropathological, behavioral, and transcriptional abnormalities.
Mol Neurobiol, 2022, 59(1):495-522. doi.org/10.1007/s12035-021-02610-8.
- Zurek B, Ellwanger K, Vissers LELM, Schüle R, Synofzik M, Töpf A, de Voer RM, Laurie S, Matalonga L, Gilissen C, Ossowski S, 't Hoen PAC, Vitobello A, Schulze-Hentrich JM, Riess O, Brunner HG, Brookes AJ, Rath A, Bonne G, Gumus G, Verloes A, Hoogerbrugge N, Evangelista T, Harmuth T, Swertz M, Spalding D, Hoischen A, Beltran S, Graessner H; Solve-RD consortium.
Solve-RD: systematic pan-European data sharing and collaborative analysis to solve rare diseases.
Eur J Hum Genet, 2021 Jun 1. doi.org/10.1038/s41431-021-00859-0.
Hentrich T, Koch A, Weber N, Kilzheimer A, Burkhardt S, Rall K, Casadei N, Kohlbacher O, Riess O, Schulze-Hentrich JM, Brucker SY.
The endometrial transcription landscape of MRKH syndrome.
Front Cell Dev Biol, 2020, 8:572281. doi.org/10.3389/fcell.2020.572281.Hentrich T, Wassouf Z, Ehrhardt C, Haas E, Mills JD, Aronica E, Outeiro TF, Hübener-Schmid J, Riess O, Casadei N, Schulze-Hentrich JM.
Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson’s disease patients.
Aging (Albany NY), 2020, 12(19):18889-18906. https://doi.org/10.18632/aging.103935.Secker KA , Bruns L, Keppeler H, Jeong J, Hentrich T, Schulze-Hentrich JM, Mankel B, Fend F, Schneidawind D, Schneidawind C.
Only Hematopoietic Stem and Progenitor Cells From Cord Blood Are Susceptible to Malignant Transformation by MLL-AF4 Translocations.
Cancers (Basel), 2020, 12(6):E1487. doi.org/10.3390/cancers12061487.Secker KA, Bloechl B, Keppeler H, Duerr-Stoerzer S, Schmid H, Schneidawind D, Jeong J, Hentrich T, Schulze-Hentrich JM, Schneidawind C.
MAT2A as Key Regulator and Therapeutic Target in MLLr Leukemogenesis.
Cancers (Basel), 2020, 12(5):1342. doi.org/10.3390/cancers12051342.Cheng F, Walter M, Wassouf Z, Hentrich T, Casadei N, Schulze-Hentrich JM, Barbuti P, Krueger R, Riess O, Grundmann-Hauser K, Ott T.
Unraveling Molecular Mechanisms of THAP1 Missense Mutations in DYT6 Dystonia.
J Mol Neurosci, 2020, 70(7):999-1008. doi.org/10.1007/s12031-020-01490-2. Yu-Taeger L, Ott T, Bonsi P, Tomczak C, Wassouf Z, Martella G, Sciamanna G, Imbriani P, Ponterio G, Tassone A, Schulze-Hentrich JM, Goodchild R, Riess O, Pisani A, Grundmann-Hauser K, Nguyen HP.
Impaired dopamine- and adenosine-mediated signaling and plasticity in a novel rodent model for DYT25 dystonia.
Neurobiol Dis, 2020, 134:104634. doi.org/10.1016/j.nbd.2019.104634.
Singh Y, El-Hadidi M, Matthes J, Wassouf Z, Schulze-Hentrich JM, Kohlhofer U, Quintanilla-Martinez de Fend L, Huson D, Riess O, Casadei N.
Enriched environmental conditions modify the gut microbiome composition and fecal markers of inflammation in Parkinson’s disease.
Front Neurosci, 2019, 13:1032. doi.org/10.3389/fnins.2019.01032.Secker KA, Keppeler H, Duerr-Stoerzer S, Schmid H, Schneidawind D, Hentrich T, Schulze-Hentrich JM, Mankel B, Fend F, Schneidawind C.
Inhibition of DOT1L and PRMT5 promote synergistic anti-tumor activity in a human MLL leukemia model induced by CRISPR/Cas9.
Oncogene, 2019, 38(46):7181-7195. doi.org/10.1038/s41388-019-0937-9.Wassouf Z, Hentrich T, Casadei N, Jaumann M, Knipper M, Riess O, Schulze-Hentrich JM.
Distinct Stress Response and Altered Striatal Transcriptome in Alpha-Synuclein Overexpressing Mice.
Front Neurosci, 2019, 12:1033. doi.org/10.3389/fnins.2018.01033
- Hentrich T, Wassouf Z, Riess O, Schulze-Hentrich JM.
SNCA overexpression disturbs hippocampal gene expression trajectories in midlife.
Aging (Albany NY), 2018, 10(12):4024-4041. doi.org/10.18632/aging.101691 - Paiva I, Jain G, Gotovac Jerčić K, Hentrich T, Kerimoglu C, Pinho R, Szegő EM, Burkhardt S, Capece V, Halder R, Islam R, Xylaki M, Caldi Gomes LA, Roser AE, Lingor P, Schulze-Hentrich JM, Borovečki F, Fischer A, Outeiro TF.
Transcriptional deregulation and ER-Golgi impairment in models of Parkinson's disease.
Neurobiol Dis, 2018, 119:121-135. doi.org/10.1016/j.nbd.2018.08.001. - Wassouf Z, Hentrich T, Samer S, Rotermund C, Kahle PJ, Ehrlich I, Riess O, Casadei N, Schulze-Hentrich JM.
Environmental enrichment prevents transcriptional disturbances induced by alpha-synuclein overexpression.
Front Cell Neurosci, 2018, 12:112. doi.org/10.3389/fncel.2018.00112. - Novati A, Hentrich T, Wassouf Z, Weber JJ, Yu-Taeger L, Déglon N, Nguyen HP, Schulze-Hentrich JM.
Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease.
Sci Rep, 2018, 8(1):5803. doi.org/10.1038/s41598-018-24243-z.