Publications

  • Knaup LK, Steiger D, Ulrich K (2026) Generating recombinant citrate synthase as substrate to study the function of molecular chaperones. pre-print at SSRN, https://ssrn.com/abstract=7273908
  • Dempsey B, R Dubrall, O Chan, KJ Lapacz, J Riemer, U Jakob, K Ulrich (2024) A dynamic redox switch turns TRC40 into a chaperone protecting human cells against ATP-depleting, oxidative stress. bioRxiv, 2024.07. 10.602939
  • Grégoire S, Grégoire J, Yang Y, Capitani S, Joshi M, Sarvan S, Zaker A, Ning Z, Figeys D, Ulrich K, Brunzelle JS, Mer A, Couture JF (2024) Structural insights into an atypical histone binding mechanism by a PHD finger. Structure 32 (9), 1498-1506. e4
  • Rothemann RA, Stobbe D, Hoehne‐Wiechmann MN, Murschall LM, Peker E, Knaup LK, Racho J, Habich M, Gerlich S, Lapacz KJ, Ulrich K, Riemer J. Interaction with the cysteine‐free protein HAX1 expands the substrate specificity and function of MIA40 beyond protein oxidation. The FEBS Journal 291 (24), 5506-5522
  • Ulrich K (2023) Redox-regulated chaperones in cell stress responses. Biochem Soc Trans BST20221304
  • Ulrich K,Farkas A, Chan O, Katamanin O, Schwappach B, Jakob U (2022) From guide to guard – Activation mechanism of the stress-sensing chaperone Get3. Mol Cell 82(17):3226-3238.e7
  • Meredith JD, Chapman I, Ulrich K, Sebastian C, Stull F, Gray MJ (2022) Escherichia coli RclA is a highly active hypothiocyanite reductase. PNAS Jul 26;119(30):e2119368119
  • Ulrich K, Schwappach B, Jakob U (2020) Thiol-based switching mechanisms of stress-sensing chaperones. Biol Chem 402(3):239-252
  • Becker SH, Ulrich K, Dhabaria A, Ueberheide B, Beavers W, Skaar E, Iyer L, Aravind L, Jakob U, Darwin KH (2020) Mycobacterium tuberculosis Rv0991c is a novel redox-regulated molecular chaperone. mBio 11(4):e01545-20
  • BazopoulouD, KnoeflerD, Zheng Y, Ulrich K, OlesonB, Xie L, Kim M, KaufmannA, LeeY, DouY, Chen Y, QuanS, JakobU (2019) Developmental ROS individualizes organismal stress resistance and lifespan. Nature 576 (7786): 301-305
  • Ulrich K and Jakob U (2019) The role of thiols in antioxidant systems. Free Radic Biol Med 140: 14-27
  • Currier R B*, Ulrich K*, Leroux A E*, Dirdjaja N, Deambrosi M, Bonilla M, Ahmed Y L, Adrian L, Antelmann H, Jakob U, Comini M A, Krauth-Siegel R L (2019) An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone. PLoS Pathog 15(9):e1008065
  • Ebersoll S, Musunda B, Schmenger T, Dirdjaja N, Bonilla M, Manta B, Ulrich K, Comini M A, Krauth-Siegel R L (2018) A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes. Redox Biol15:532-547
  • Ulrich K, Finkenzeller C, Merker S, Rojas F, Matthews K, Ruppert T, Krauth-Siegel R L (2017) Stress-induced protein S-glutathionylation and S-trypanothionylation in African trypanosomes – a quantitative redox proteome and thiol analysis. Antioxid Redox Signal 27(9): 517-533
  • Preveti S, Ettari R, Cosconati S, Amendola G, Chouchene K, Wagner, A., Hellmich, U A, Ulrich K, Krauth-Siegel R L, Wich P R, Schmid I, Schirmeister T, Gut J, Rosenthal P J, Grasso S, and Zappalà M (2017) Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs). J Med Chem 60(16): 6911-6923