Synthese peptidischer Naturstoffe

  • C. Quirin, U. Kazmaier, "Synthesis of Chlamydocin via Chelate-Claisen Rearrangement", Eur. J. Org. Chem. 2009, 371-377.
  • A. Ullrich, Y. Chai, D. Pistorius, Y. A. Elnakady, J. E. Herrmann, K. J. Weissman, U. Kazmaier, and R. Müller, "Pretubulysin, a potent and chemically-accessible tubulysin precursor from Angiococcus disciformis", Angew. Chem. 2009, 121, 4486–4489; Angew. Chem. Int. Ed. 2009, 47, 4422–4425.
  • A. Ullrich, J. Herrmann, R. Müller, U. Kazmaier, "Synthesis and biological evaluation of pretubulysin and derivatives", Eur. J. Org. Chem. 2009, 6367–6378.
  • D. Gawas, U. Kazmaier, "Diastereotopos-differentiating allylic alkylation as key step in natural product synthesis", Org. Biomol. Chem. 2010, 8, 457–462.
  • D. Pistorius, A. Ullrich, S. Lucas, R. W. Hartmann, U. Kazmaier, R. Müller, "Biosynthesis of 2-alkyl-4(1H)-quinolones in Pseudomonas auruginosa: Potential for interference with pathogenicity", ChemBioChem 2011, 850–853.
  • J. L. Burkhart, R. Müller, U. Kazmaier, "Syntheses and Evaluation of Simplified Pretubulysin Analogues", Eur. J. Org. Chem. 2011, 3050–3059.
  • J. L. Burkhart, U. Kazmaier, "A straightforward approach towards protected (S)-dolaphenine (Doe), the unusual amino acid of dolastatin 10", Synthesis 2011, 4033–4036.
  • J. L. Burkhart, U. Kazmaier, "A straightforward click-approach towards pretubulysin-analogues", RSC Advances 2012, 2, 3785–3790.
  • S. Ackermann, H.-G. Lerchen, D. Häbich, A. Ullrich, U. Kazmaier, "Synthetic studies towards Bottromycin", Beilstein J. Org. Chem. 2012, 8, 1652–1656.
  • U. Kazmaier, A. Ullrich, J. Hoffmann, "Synthetic Approaches towards Tubulysins and their Derivatives", Open Nat. Prod. J. 2013, 6, 12−30.
  • L. Karmann, K. Schulz, J. Herrmann, R. Müller, U. Kazmaier, "Total Syntheses and Biological Evaluation of Miuraenamides", Angew. Chem. 2015, 127, 4585–4590; Angew. Chem. Int. Ed.2015, 54, 4502–4507.
  • D. Becker, U. Kazmaier, "Synthesis of Simplified Halogenated Chondramide Derivatives as new Actin-binding Agents", Eur. J. Org. Chem. 2015, 2591–2602.
  • J. Hoffmann, J. Gorges, L. Junk, U. Kazmaier, "Synthesis of Pretubulysin-Derivatives via the TubUgi-Approach", Org. Biomol. Chem. 2015, 13, 6010–6020.
  • D. Becker, U. Kazmaier, "Synthesis and Biological Evaluation of Dichlorinated Chondramide Derivatives", Eur. J. Org. Chem. 2015, 4198–4213.
  • P. Barbie, U. Kazmaier, "Total Synthesis of Cyclomarin A, a Marine Cycloheptapeptide with anti-Tuberculosis and anti-Malaria Activity", Org. Lett. 2016, 18, 204−207.
  • P. Barbie, U. Kazmaier, "Total synthesis of cyclomarins A, C and D, marine cyclopeptides with interesting anti tuberculosis and anti malaria activitites", Org. Biomol. Chem. 2016, 14, 6036−6054.
  • P. Barbie, U. Kazmaier, "Total synthesis of desoxycyclomarin C and the cyclomarazines A and B", Org. Biomol. Chem. 2016, 14, 6055−6064.
  • P. Servatius, U. Kazmaier, "Total synthesis of the natural HDAC inhibitor Cyl-1", Org. Biomol. Chem. 2018, 16, 3464–3472.
  • J. Gorges, U. Kazmaier, "Matteson Homologation-based Total Synthesis of Lagunamide A", Org. Lett. 2018, 20, 2033−2036.
  • L. Junk, U. Kazmaier, "Totalsynthese und Konfigurationsrevision der Keramamide A und L aus gemeinsamer Vorstufe via späte Indolsynthese", Angew. Chem. 2018, 130, 11602−11606; Angew. Chem. Int. Ed. 2018, 57, 11432−11435.
  • P. Servatius, U. Kazmaier, "Total Synthesis of Trapoxin A, a fungal HDAC-inhibitor from Helicoma ambiens", J. Org. Chem. 2018, 83, 11341−11349.
  • J. Gorges, L. Kjaerulff, F. Panter, T. Hoffmann, U. Kazmaier, R. Müller, "Structure, total synthesis and biosynthesis of Chloromyxamides - myxobacterial tetrapeptides featuring an uncommon 6-chloromethyl-5-methoxypipecolic acid building block", Angew. Chem. 2018, 130, 14466–14471; Angew. Chem.Int.Ed. 2018, 57, 14270–14275.
  • S. Kappler, L. Karmann, C. Prudel, J. Herrmann, G. Caddeu, R. Müller, A. M. Vollmar, S. Zahler, U. Kazmaier, "Synthesis and biological evaluation of (modified) miuraenamides", Eur. J.Org. Chem. 2018, 6952–6965.
  • A. Kiefer, U. Kazmaier, "Syntheses of Cyclomarins – Interesting Marine Natural Products with Distinct Mode of Action towards Malaria and Tuberculosis", Synthesis 2019, 51, 107–121.
  • L. Junk, U. Kazmaier, "Total Synthesis and Configurational Revision of Mozamide A – a Hydroxy-Brunsvicamide", J. Org. Chem. 2019, 84, 2489–2500.
  • P. Servatius, T. Stach, U. Kazmaier, "Total synthesis of luminmycin A, a cryptic natural product from Photorhabdus luminescens", Eur. J. Org. Chem. 2019, 3163–3168.
  • A. Kiefer, C. D. Bader, J. Held, A. Esser, J. Rybniker, M. Empting, R. Müller, U. Kazmaier, "Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Myco­bacterium Tuberculosis and Plasmodium Falsiparum", Chem. Eur. J. 2019, 25, 8894–8902.