Publikationen

Für eine Aufstellung der Publikationen von Prof. Dr. C. Roy D. Lancaster bei der U.S. National Library of Medicine (PubMed), klicken Sie bitte hier:

Pubmed

2022

Carius Y, Hutter M, Kiss F, Bernhardt R*, Lancaster CRD* (2022)
Structural comparison of the cytochrome P450 enzymes CYP106A1 and CYP106A2 provides insight into their differences in steroid conversion.
FEBS Lett. 596,  3133-3144,
https://dx.doi.org/10.1002/1873-3468.14502 .

Carius Y, Ries F, Gries K, Trentmann O, Lancaster CRD*, Willmund F* (2022)
Structural features of chloroplast trigger factor determined at 2.6 Å resolution.
Acta Crystallogr D Struct Biol. 78, 1259-1272,
https://dx.doi.org/10.1107/S2059798322009068 .

Suiwal S, Dembla M, Schwarz K, Katiyar R, Jung M, Carius Y, Maxeiner S, Lauterbach MA, Lancaster CRD, Schmitz F. (2022)
Ciliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses.
Int J Mol Sci. 23, 7135,  https://dx.doi.org/10.3390/ijms23137135.

Bazzone A*, Tesmer L, Kurt D, Kaback HR, Fendler K, Madej MG* (2022) Investigation of sugar binding kinetics of the E. coli sugar/H+ symporter XylE using solid-supported membrane-based electrophysiology. J Biol Chem 298, 101505, https://doi.org/10.1016/j.jbc.2021.101505 .

2020

Klein M¹, Deniz E¹, Heit S¹, Wille G, Mäntele W, Lancaster CRD (2020)
Proton-Coupled Electron Transport in Two Distinct CYBASC Paralogs of Arabidopsis thaliana: A Comparative Characterization of Highly Conserved Tyrosine and Lysine Residues.
 Biochemistry 59, 2328-2339,
https://dx.doi.org/10.1021/acs.biochem.0c00155 .

2018

Lancaster, C.R.D. (2018) Respiratory Chain Complex II and Succinate:Quinone Oxidoreductases. In: Reference Module in Biomedical Sciences. Elsevier, https://dx.doi.org/10.1016/B978-0-12-801238- 3.11139-0.
 

2017

Ries, F.¹, Carius, Y.¹, Rohr, M., Gries, K., Keller, S., Lancaster, C.R.D.^*, Willmund, F.^* (2017) Structural and molecular comparison of bacterial and eukaryotic trigger factors. Sci. Rep. 7, 10680, http://www.nature.com/articles/s41598-017-10625-2 .

Lancaster, C.R.D., Betz, Y.M., Heit, S., Lafontaine, M.A. (2017) Transmembrane electron and proton transfer in diheme-containing succinate:quinone oxidoreductases. Isr. J. Chem. 57: 370-380. doi: 10.1002/ijch.201600139
 

2016

Janocha S, Carius Y, Hutter M, Lancaster CRD, Bernhardt R. (2016) Crystal structure of CYP106A2 in substrate-free and substrate-bound form. Chembiochem. 17: 852–860. doi: 10.1002/cbic.201500524

Salamanca-Pinzon SG, Khatri Y, Carius Y, Keller L, Müller R, Lancaster CRD, Bernhardt R (2016) Structure-function analysis for the hydroxylation of Δ4 C21-steroids by the myxobacterial CYP260B1. FEBS Lett. 590: 1838-1851. doi: 10.1002/1873-3468.12217

Khatri Y, Carius Y, Ringle M, Lancaster CRD, Bernhardt R (2016) Structural characterization of CYP260A1 from Sorangium cellulosum to investigate the 1alpha-hydroxylation of a mineralocorticoid. FEBS Lett. 590: 4638-4648. doi: 10.1002/1873-3468.12479 
 

2015

Lafontaine, M., Lancaster, C.R.D. (2015) An unconventional anaerobic membrane protein production system based on Wolinella succinogenes. Methods Enzymol. 556: 99-121. doi: 10.1016/bs.mie.2014.12.026.

Nickel AG, von Hardenberg A, Hohl M, Löffler JR, Kohlhaas M, Becker J, Reil JC, Kazakov A, Bonnekoh J, Stadelmaier M, Puhl SL, Wagner M, Bogeski I, Cortassa S, Kappl R, Pasieka B, Lafontaine M, Lancaster CRD, Blacker TS, Hall AR, Duchen MR, Kästner L, Lipp P, Zeller T, Müller C, Knopp A, Laufs U, Böhm M, Hoth M, Maack C (2015) Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure. Cell Metab. 22: 472-484. doi: 10.1016/j.cmet.2015.07.008. 
 

2014

Auerbach, D., Klein, M., Franz, S., Carius, Y., Lancaster, C.R.D., Jung, G. (2014) Replacement of Highly Conserved E222 by the Photostable Non-photoconvertible Histidine in GFP. ChemBioChem 15: 1404-1408.
 

2013

Lancaster, C.R.D. (2013) Respiratory Chain Complex II and Succinate: Quinone Oxidoreductases. In: The Encyclopedia of Biological Chemistry, Vol. 4 (Lennarz, W.J., Lane, M.D., eds.), Elsevier, Waltham, MA, pp. 92-97.

Lancaster, C.R.D. (2013) Purple Bacteria: Photosynthetic Reaction Centers. In: The Encyclopedia of Biological Chemistry, Vol. 3 (Lennarz, W.J., Lane, M.D., eds.), Elsevier, Waltham, MA, pp. 700-707.

Müller F.G., Lancaster C.R.D. (2013) Crystallization of membrane proteins. Methods Mol Biol 1033, 67-83.

Lancaster, C.R.D. (2013) The di-heme family of respiratory complex II enzymes. Biochim Biophys Acta - Bioenergetics 1827, 679-687.

Nasiri, H. R., Madej, M. G., Panisch, R., Lafontaine, M., Bats, J. W., Lancaster, C. R. D. and Schwalbe, H. (2013) Design, Synthesis, and Biological Testing of Novel Naphthoquinones as Substrate-Based Inhibitors of the Quinol:Fumarate Reductase from Wolinella succinogenes. J. Med. Chem. 56: 9530-9541.
 

2012

Cenacchi, L., Busch, M., Schleidt, P.G., Müller, F.G., Stumpp, T.V.M., Mäntele, W., Trost, P., Lancaster, C.R.D. (2012) Heterologous production and characterisation of two distinct dihaem-containing membrane integral cytochrome b561 enzymes from Arabidopsis thaliana in Pichia pastoris and Escherichia coli cells. Biochim. Biophys. Acta - Biomembranes 1818, 679–688.

Herzog, E., Gu, W., Juhnke, H.D., Haas, A.H., Mäntele, W., Simon, J., Helms, V., Lancaster, C.R.D. (2012) Hydrogen-bonded networks along and bifurcation of the E-pathway in quinol:fumarate reductase. Biophysical J. 103, 1305-1314. 
 

2011

Lancaster, C.R.D. (2011) The superfamily of succinate:quinone oxidoreductases and its implications for the cyanobacterial enzymes. In: Bioenergetic Processes of Cyanobacteria (Peschek, G.A., Obinger, C., Renger, G., eds.), Springer, Dordrecht, NL, pp 469-511
 

2009

Sreeramulu,S., Jonker, H.R.A., Langer,T., Richter,C., Lancaster,C.R.D. and Schwalbe. H. (2009) The Human Cdc37·Hsp90 Complex Studied by Heteronuclear NMR Spectroscopy. J. Biol. Chem. 284, 3885-3896

Juhnke, H.D., Hiltscher, H., Nasiri, H. R., Schwalbe, H., Lancaster, C.R.D. (2009) Production, Characterization, and Determination of the Real Catalytic Properties of the Putative 'Succinate Dehydrogenase' from Wolinella succinogenes. Mol. Microbiol. 71, 1088-1101

Nasiri, H.R., Panisch, R., Madej, M.G., Bats, J.W., Lancaster, .C.R.D., Schwalbe, H. (2009) The correlation of cathodic peak potentials of vitamin K(3) derivatives and their calculated electron affinities The role of hydrogen bonding and conformational changes. Biochim. Biophys. Acta - Bioenergetics 1787, 601-608

Madej, M.G., Müller, F.G., Ploch, J., Lancaster, C.R.D.(2009) Limited reversibility of transmembrane proton transfer assisting transmembrane electron transfer in a dihaem-containing succinate:quinone oxidoreductase. Biochim Biophys Acta - Bioenergetics 1787, 593-600
 

2008

Kozlova, M.A., Juhnke, H.D., Cherepanov, D.A., Lancaster, C.R.D., Mulkidjanian, A.Y. (2008) Proton transfer in the photosynthetic reaction center of Blastochloris viridis. FEBS Lett. 582, 238-242.

Lancaster, C.R.D., Herzog, E., Juhnke, H.D, Madej, M.G., Müller, F.G., Paul, R., Schleidt, P.G. (2008) Electroneutral and electrogenic catalysis by dihaem-containing succinate:quinone oxidoreductases. Biochem. Soc. Trans. 36, 996-1000
 

2007

Lancaster, C. R. D., Hunte, C., Kelley III, J., Trumpower, B.L., Ditchfield, R. (2007) A comparison of stigmatellin conformations, free and bound to the photosynthetic reaction center and the cytochrome bc1 complex. J. Mol. Biol. 368, 197-208.

Lancaster, C.R.D. (2007) Structures of Reaction Centers in Anoxygenic Bacteria. In: Primary Processes of Photosynthesis. Principles and Apparatus. Part 2: Reaction Centers/Photosystems, Electron Transport Chains, Photophosphorylation and Evolution (Renger, G., Ed.), Royal Society of Chemistry, Cambridge, pp. 5-56. 
 

2006

Mileni, M., MacMillan, F., Tziatzios, C. Zwicker, K., Haas, A.H., Mäntele, W., Simon, J., Lancaster, C.R.D.(2006) Heterologous production in Wolinella succinogenes and characterisation of the quinol:fumarate reductase enzymes from Helicobacter pylori and Campylobacter jejuni. Biochem. J. 395: 191-201.

Herzog, E., Frigato, T., Helms V., Lancaster, C.R.D. (2006) Energy barriers of proton transfer reactions between amino acid side chain analogs and water from ab initio calculations. J. Comput. Chem. 27: 1534-1547.

Lancaster, C.R.D., Haas, A.H., Madej, M.G., Mileni, M. (2006) Recent progress on obtaining theoretical and experimental support for the "E-pathway hypothesis" of coupled transmembrane electron and proton transfer in dihaem-containing quinol:fumarate reductase. (Special Issue: Proton Transfer Reactions) Biochim. Biophys. Acta, Bioenerg. 1757: 988-995.

Madej, M.G., Nasiri, H.R., Hilgendorff, N.S., Schwalbe H., Lancaster, C.R.D. (2006) Evidence for transmembrane proton transfer in a dihaem-containing membrane protein complex. EMBO J. 25, 4963-4970.

Nasiri, H.R., Madej, M.G., Lancaster, C.R.D., Schwalbe H., Bolte M. (2006) 2-Hydroxy-2-3-(3-oxobutyl)naphtalene-1,4-dione. Acta Crystallogr., Sect C 62 , 0671-0673.

Madej, M.G., Nasiri, H.R., Hilgendorff, N.S., Schwalbe H., Unden, G., Lancaster, C.R.D. (2006) Experimental evidence for proton-motive force-dependent catalysis by the diheme-containing succinate:menaquinone oxidoreductase from the Gram-positive bacterium Bacillus licheniformis. Biochemistry 45, 15049-15055.
 

2005

Fufezan, C., Drepper, F., Juhnke, H.D., Lancaster, C.R.D., Un, S., Rutherford, A.W., and Krieger-Liszkay, A. (2005) Herbicide-induced changes in charge recombination and redox potential of QA in the T4 mutant of Blastochloris viridis. Biochemistry 44: 5931-5939.

Haas, A.H., Sauer, U.S., Groß, R., Simon, J., Mäntele, W., Lancaster, C.R.D. (2005) FTIR Difference Spectra of Wolinella succinogenes quinol:fumarate reductase support a key role of Glu C180 within the "E-Pathway Hypothesis" of Coupled Transmembrane Electron and Proton Transfer. Biochemistry 44: 13949 - 13961.

Lancaster, C.R.D., Sauer, U.S., Groß, R., Haas, A.H., Graf, J., Schwalbe, H., Mäntele, W., Simon, J., Madej, M.G.(2005) Experimental support for the "E-pathway hypothesis" of coupled transmembrane e- and H+ transfer in dihemic quinol:fumarate reductase. Proc. Natl. Acad. Sci. U.S.A. 102: 18860 - 18865.

Mileni, M., Haas, A.H., Mäntele, W., Simon, J., Lancaster, C.R.D.(2005) Probing Heme Propionate Involvement in Transmembrane Proton Transfer Coupled to Electron Transfer in Dihemic Quinol:Fumarate Reductase by 13C-Labeling and FTIR Difference Spectroscopy. Biochemistry 44: 16718 - 16728.
 

2004

Gross, R., Pisa, R., Sänger, M., Lancaster, C.R.D., Simon, J. (2004) Characterization of the menaquinone reduction site in the diheme cytochrome b membrane anchor of Wolinella succinogenes NiFe hydrogenase J. Biol. Chem. 279: 274-281.

Lancaster, C.R.D. (2004) Structure and function of succinate:quinone oxidoreductases and the role of quinol:fumarate reductases in fumarate respiration. In: Zannoni, D. (Ed.) Respiration in Archaea and Bacteria Volume 1: Diversity of Prokaryotic Electron Transport Carriers. Kluwer Scientific, Dordrecht, The Netherlands, pp. 57-85. 

Lancaster, C.R.D. (2004) Purple Bacteria: Photosynthetic Reaction Centers. In: Encyclopedia of Biological Chemistry (Lennarz, W.J., Lane, M.D., eds.), Elsevier, Oxford, U.K., Vol. 3, 586-594.

Lancaster, C.R.D. (2004) Respiratory Chain Complex II and Succinate:Quinone Oxidoreductases. In: Encyclopedia of Biological Chemistry (Lennarz, W.J., Lane, M.D., eds.), Elsevier, Oxford, U.K., Vol. 3, 681-687.

Lancaster, C.R.D. (2004) Ion pump in the movies. Nature 432: 286-287.

Haas, A.H., Lancaster, C.R.D. (2004) Calculated Coupling of Transmembrane Electron and Proton Transfer in Dihemic Quinol:Fumarate Reductase. Biophys J. 87: 4298-4315.
 

2003

Lancaster, C.R.D. (2003) Crystallization of Wolinella succinogenes quinol:fumarate reductase. In: Membrane Protein Purification and Crystallization. 2nd edition. Hunte, C., Schägger, H., von Jagow, G. (Eds.) Academic Press, San Diego, CA, U.S.A., pp. 219-228. 

Lancaster, C.R.D. (2003) The structure of Wolinella succinogenes quinol:fumarate reductase and its relevance to the superfamily of succinate:quinone oxidoreductases. Adv. Prot. Chem. 63: 131-149.

Lancaster, C.R.D. (2003) The role of electrostatics in proton-conducting membrane protein complexes. FEBS Lett. 545: 52-60.

Lancaster, C.R.D. (2003) Crystallization of Wolinella succinogenes quinol:fumarate reductase in three crystal forms. Iwata, S. (Ed.) Methods and Results in Membrane Protein Crystallization. University Line, La Jolla, CA, U.S.A, pp. 177-192.

Lancaster, C.R.D. (2003) Wolinella succinogenes quinol:fumarate reductase and its comparison to E. coli succinate:quinone reductase. FEBS Lett. 555: 21-28.
 

2002

Lancaster, C.R.D. (2002) Succinate:quinone oxidoreductases - an overview (Editorial) Biochim. Biophys. Acta Bioenergetics 1553: 1-6.

Kröger, A., Biel, S., Simon, J., Gross, R., Unden, G., Lancaster, C.R.D. (2002) Fumarate respiration of Wolinella succinogenes: enzymology, energetics, and coupling mechanism. Biochim. Biophys. Acta Bioenergetics 1553: 23-38.

Lancaster, C.R.D., Simon, J. (2002) Succinate: quinone oxidoreductases from ε-proteobacteria. Biochim. Biophys. Acta Bioenergetics 1553: 84-101

Barquera, B., Hellwig, P., Zhou, W., Morgan, J.E., Häse, C.C., Gosink, K.K., Nilges, M., Bruesehoff, P.J., Roth, A., Lancaster, C.R.D., Gennis, R.B. (2002) Purification and characterization of the recombinant Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae. Biochemistry 41: 3781-3789.

Lancaster, C.R.D. (2002) A P-type ion pump at work. Nature Struct. Biol. 9: 643-645.

Lancaster, C.R.D. (2002) Wolinella succinogenes quinol:fumarate reductase - 2.2 Å resolution crystal structure and the E-pathway hypothesis of coupled transmembrane proton and electron transfer Biochim. Biophys. Acta Biomembranes 1565: 215-231.
 

2001

Lancaster, C.R.D., Groß, R., Simon, J. (2001) A third crystal form of Wolinella succinogenes quinol:fumarate reductase reveals domain closure at the site of fumarate reduction. Eur. J. Biochem. 268: 1820-1827.

Zachariae, U., Lancaster, C.R.D. (2001) Proton uptake associated with the reduction of the primary quinone QA influences the binding site of the secondary quinone QB in Rhodopseudomonas viridis photosynthetic reaction centres. Biochim. Biophys. Acta Bioenergetics 1505: 280-290.

Lancaster, C.R.D., Michel, H. (2001) Photosynthetic reaction centres of purple bacteria. In: Handbook of Metalloproteins (Wieghardt, K., Huber, R., Poulos, T., Messerschmidt, A., eds.), Volume 1, Wiley, Chichester, U.K., pp. 119-135. 

Lancaster, C.R.D. (2001) Succinate:quinone oxidoreductases. In: Handbook of Metalloproteins (Wieghardt, K., Huber, R., Poulos, T., Messerschmidt, A., eds.), Volume 1, Wiley, Chichester, U.K., pp. 379-401.

Bartoschek, S., Johansson, M., Geierstanger, B.H., Okun, J.G., Lancaster, C.R.D., Humpfer, E., Yu, L., Yu, C.A., Griesinger, C., Brandt, U. (2001) Three molecules of ubiquinone bind specifically to mitochondrial cytochrome bc1 complex J. Biol. Chem. 276: 35231-35234

Lancaster, C.R.D. (2001) Succinate:quinone oxidoreductases - What can we learn from Wolinella succinogenes quinol:fumarate reductase? FEBS Lett. 504: 133-141.
 

2000

Lancaster, C.R.D., Bibikova, M.V., Sabatino, P., Oesterhelt, D., Michel, H. (2000) Structural basis of the drastically increased initial electron transfer rate in the reaction center from a Rhodopseudomonas viridis mutant described at 2.00-Å resolution. J. Biol. Chem. 275: 39364-39368 .

Lancaster, C.R.D., Groß, R., Haas, A., Ritter M., Mäntele W., Simon, J., Kröger, A. (2000) Essential role of Glu-C66 for menaquinol oxidation indicates transmembrane electrochemical potential generation by Wolinella succinogenes fumarate reductase. Proc. Natl. Acad. Sci. U.S.A. 97: 13051-13056. 

Lancaster, C.R.D., Kröger, A. (2000) Succinate: quinone oxidoreductases: new insights from X-ray crystal structures. Biochim. Biophys. Acta Bioenergetics 1459: 422-431.
 

1999

Lancaster, C.R.D., Michel, H. (1999) Refined Crystal Structures of Reaction Centres from Rhodopseudomonas viridis in Complexes with the Herbicide Atrazine and Two Chiral Atrazine Derivatives also Lead to a New Model of the Bound Carotenoid. J. Mol. Biol. 286: 883-898

Lancaster, C.R.D. (1999) Quinone-binding sites in membrane proteins: what can we learn from the Rhodopseudomonas viridis reaction centre? Biochem. Soc. Trans. 27: 591-596.

Lancaster, C.R.D., Kröger, A., Auer, M., Michel, H. (1999) Structure of fumarate reductase from Wolinella succinogenes at 2.2 Å resolution. Nature 402, 377-385 (1999). 
 

1998

Lancaster, C.R.D. (1998) Ubiquinone reduction and protonation in photosynthetic reaction centres from Rhodopseudomonas viridis - X-ray structures and their functional implications. Biochim. Biophys. Acta Bioenergetics 1365: 143-150.

Kannt, A., Lancaster, C.R.D., Michel, H. (1998) The coupling of electron transfer and proton translocation: electrostatic calculations on Paracoccus denitrificans cytochrome c oxidase. Biophys. J. 74: 708-721.

Kannt, A., Lancaster, C.R.D., Michel, H. (1998) The role of electrostatic interactions for cytochrome c oxidase function. J. Bioenerg. Biomembr. 30: 81-87

Gross, R., Simon, J., Lancaster, C.R.D., Kröger, A. (1998) Identification of histidine residues in Wolinella succinogenes hydrogenase that are essential for menaquinone reduction by H2. Mol. Microbiol. 30: 639-646. 
 

1997

Lancaster, C.R.D., Michel, H. (1997) The coupling of light-induced electron transfer and proton uptake as derived from crystal structures of reaction centres from Rhodopseudomonas viridis modified at the binding site of the secondary quinone, QB. Structure 5: 1339-1359.
 

1996

Lancaster, C.R.D., Michel, H. (1996) Three-dimensional structures of photosynthetic reaction centers (Minireview). Photosynth. Res. 48: 65-74. 

Lancaster, C.R.D., Michel, H., Honig, B., Gunner, M.R. (1996) Calculated coupling of electron and proton transfer in the photosynthetic reaction center of Rhodopseudomonas viridis. Biophys. J. 70: 2469-2492.