Endothelial dysfunction, atherosclerosis

Selected publications

  • Linnenberger R, Hoppstädter J, Wrublewsky S, Ampofo E, Kiemer AK. 2021. Statins and bempedoic acid: Different actions of cholesterol inhibitors on macrophage activation. Int J Mol Sci 22:12480 
  • Hoppstädter J, Valbuena Perez JV, Linnenberger R, Dahlem C, Legroux TM, Hecksteden A, Tse WKF, Flamini S, Andreas A, Herrmann J, Herr Ch, Müller R, Meyer T, Bals R, Riccardi C, Bruscoli S, Kiemer AK. 2020. The glucocorticoid-induced leucine zipper (GILZ) mediates statin-induced muscle damage. FASEB J 34:4684-470
  • Astanina K, Koch M, Jüngst C, Zumbusch A, Kiemer AK. 2015. Lipid droplets as a novel cargo of tunneling nanotubes in endothelial cells. Sci Rep 5:11453
  • Nature Video
  • Astanina K, Simon Y, Cavelius C, Petry S, Kraegeloh A, Kiemer AK. 2014. Superparamagnetic iron oxide nanoparticles impair endothelial integrity and inhibit nitric oxide production. Acta Biomater 10:4896-4911
  • Hahn RT, Hoppstädter J, Hirschfelder K, Hachenthal N, Diesel B, Kessler SM, Huwer H, Kiemer AK. 2014. Downregulation of the glucocorticoid-induced leucine zipper (GILZ) promotes vascular inflammation. Atherosclerosis 234:391-400
  • Diesel B, Ripoche N, Tierling S, Walter J, Kiemer AK. 2012. Inflammation-induced upregulation of TLR2 expression in human endothelial cells is independent of differential methylation in the TLR2 promoter CpG island. Innate Immun 18:112-123
  • Fürst R, Kuebler WM, Brueckl C, Zahler S, Krötz F, Görlach A, Vollmar AM, Kiemer AK. 2005. Atrial Natriuretic Peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2 activation. Circ Res 96:43-53