Chair for Genetics and Epigenetics

Our research group focuses on the investigation of epigenetic phenomena associated with development and disease. The following research areas are of particular interest: Characterization and functional analysis of imprinted genes, Epigenetic mapping of genomes (Epigenomics), Research into epigenetic programs in stem cells, Evolution of epigenetic mechanisms. We use and develop state-of-the-art molecular methods and bioinformatic data analysis pipelines and we produce large molecular data sets in our own Sequencing Facility. As coodinator of the German Epigenome Program we significantly contributed to the first epigenetic atlas of all human cell types. We are member of the International Human Epigenome Consortium.



GHGA Symposium 2023

As part of its Annual Meeting, the German Human Genome Phenome Archive (GHGA) will hold a public symposium with the title ‘Data Infrastructures for Genomic Research in Europe on 04 October 2023.

The event will have two sessions on ‘National Infrastructure Solutions’ and ‘Trust Building and Patient Engagement in Genome Research’, including a panel discussion. Presenters include members of GHGA but also renowned experts in the field of biomedical research.

Please find more information here.




Lecture on the analysis of ancient genomes

On October 18, Janet Kelso (MPI for Evolutionary Anthropology) will talk about “The impact of gene flow between archaic and modern humans”, including likely functional consequences of Neandertal haplotypes based on genome, gene expression, and phenotype datasets.

The talk is part of a virtual lecture series hosted by the German Human Genome Phenome Archive (GHGA) that explores various aspects of data-driven medicine and its ethical, legal, and social implications.

Please find more information here.


Podcast on next generation sequencing

In a new podcast episode, Prof. Dr. Joachim Schultze (DZNE) highlights state-of-the-art sequencing technologies and their development, as well as applications such as the monitoring of viral variants.

The episode is part of the German Human Genome Phenome Archive (GHGA) science podcast titled "Der Code des Lebens” which focuses on various aspects of human genome research (in German).

The podcast and further information are available here.