Senior Professor for Genetics and Epigenetics

Our research group focuses on the investigation of epigenetic phenomena associated with development and disease. The following research areas are of particular interest: Characterization and functional analysis of imprinted genes, Epigenetic mapping of genomes (Epigenomics), Research into epigenetic programs in stem cells, Evolution of epigenetic mechanisms. We use and develop state-of-the-art molecular methods and bioinformatic data analysis pipelines and we produce large molecular data sets in our own Sequencing Facility. As coodinator of the German Epigenome Program we significantly contributed to the first epigenetic atlas of all human cell types. We are member of the International Human Epigenome Consortium.

 

Arbeitsgruppe

Group Leader

Prof. Dr. Jörn Walter

j.walter(at)mx.uni-saarland.de

0681-302-4367

 

 

Dr. Nina Gasparoni

nina.gasparoni(at)uni-saarland.de

0681-302-2296

 

Dr. Gilles Gasparoni

gillesgasparoni(at)googlemail.com

0681-302-2881

 

Dr. Kathrin Kattler

kathrin.kattler(at)googlemail.com

0681-302-2296

 

Nihit Aggarwal

nihit.aggarwal(at)uni-saarland.de

0681-302-2881

 

M.Sc. Narges Jafari

nrgjafari(at)gmail.com

0681-302-2443

 

 

M.Sc. Alea Leismann

alea.leismann(at)uni-saarland.de

0681-302-2296

 

 

NEWS

Upcoming Talk: Epigenomics and the IHEC EpiAtlas

On June 18, 2025, Jörn Walter will give a talk on “Epigenomics and the IHEC EpiAtlas.” In his presentation, he will outline the aims and current progress of the Human Epigenome Atlas, developed by the International Human Epigenome Consortium (IHEC). He will also highlight recent work on the epigenomic dynamics involved in T and B memory cell development, using multimodal sequencing and integrated bioinformatic approaches.
The talk is part of the virtual seminar series “Epigenetics and Viral Infections” organized by the EU-funded EPIVINF project.
Please find more information here.

Podcast Episode: genomDE Pilot Project

The genomDE pilot project aims to integrate genomic medicine into standard healthcare. In the latest episode of the science podcast "Der Code des Lebens" (available only in German) published by the German Human Genome-Phenome Archive (GHGA), PD Dr Andreas Till from the Federal Institute for Drugs and Medical Devices (BfArM) explains the project’s aims, structures and open questions.
The podcast and further information are available here.

Genomhäppchen: Season 2

The science podcast "Genomhäppchen" is back for its second season! In short, easy digestible 5-minute episodes, you’ll gain exciting insights into the world of genomics. The first three episodes of the new season explore fascinating topics such as wine genomics, the craziest theories about the origin of life and the giant genomes of olms.
Genomhäppchen is published by the German Human Genome Phenome Archive (GHGA). The German-language podcast is published every two weeks on all commonly used platforms.
Please find further information here.

Research and Scientific Activitites