Information for
Quick links
Faculties
Chair for Genetics and Epigenetics
Our research group focuses on the investigation of epigenetic phenomena associated with development and disease. The following research areas are of particular interest: Characterization and functional analysis of imprinted genes, Epigenetic mapping of genomes (Epigenomics), Research into epigenetic programs in stem cells, Evolution of epigenetic mechanisms. We use and develop state-of-the-art molecular methods and bioinformatic data analysis pipelines and we produce large molecular data sets in our own Sequencing Facility. As coodinator of the German Epigenome Program we significantly contributed to the first epigenetic atlas of all human cell types. We are member of the International Human Epigenome Consortium.
NOW AVAILABLE !!! The new genome sequencer AvitiTM by Element Biosc. in our Epigenomics Sequencing Facility !
We are pleased to announce that the AvitiTM platform (Element Biosc.) is now ready to use for internal and external users.
Please find more information about the AvitiTM and NGS applications on our Epigenomics Sequencing Facility web site.
Lecture on Human Cell Atlas
On 24 July 2024, Sarah Teichmann (Wellcome Trust Sanger Institute) will give a presentation on "(Machine) learnings for the Human Cell Atlas". She is the co-founder and co-leader of the international Human Cell Atlas consortium, which aims to create reference maps for cells across all human tissues.
The talk is part of a virtual lecture series hosted by the German Human Genome Phenome Archive (GHGA) that explores various aspects of data-driven medicine and its ethical, legal, and social implications.
Please find more information here.
New brochure: In Focus: Genomic Data
To mark the start of the model project on genome sequencing on 1 April 2024, the Gene Technology Report working group, in collaboration with the German Human Genome Archive (GHGA), has published the brochure "In Focus: Genomic Data". It explores the potential of personalised genome sequencing for rare disease and cancer research, as well as the ethical, legal and social implications.
In their chapter, Jörn Walter, Nina Gasparoni and Oliver Kohlbacher address the challenges of securely archiving and efficiently using complex genomic data. On the occasion of the brochure's release, a public evening event discussed the importance of genomic data in modern medical research and diagnostics. A video recording is available here.
The brochure is available here.