Publikationen 2025

  1. Luo Q, Quan W, Cao Q, Scheffel C, Hao W, Yang J, Furihata T, Peng G, Tang Z, Liu Y (2025). Brain-derived neurotrophic factor supports pericyte and vascular homeostasis in the aging brain. Acta Neuropathol Commun, 13(1), 246, doi:10.1186/s40478-025-02181-y.

  2. Natori Y, Sester M (2025). The role of CMV-specific cellular immunity in transplant recipients with letermovir prophylaxis: to be determined. Clin Infect Dis, ciaf633, doi:10.1093/cid/ciaf633.

  3. Teleken JL, Roma LP, Ribeiro RA, Rafacho A, Bonfleur ML (2025). Commercial glyphosate formulations exceed active ingredient toxicity via mitochondrial ROS and transcriptomic disruption. Toxicol In Vitro, 111, 106178, doi:10.1016/j.tiv.2025.106178.

  4. Portugal CC, Almeida TO, Tedim-Moreira J, Silva C, Canedo T, Galvão J, Magalhães A, Summavielle T, Bai X, Kirchhoff F, Rubinstein B, Moreira I, Costa J, Guedes J, Pinto IM, Peça J, Socodato R, Relvas JB (2025). Profilin 1 controls a microglial cytoskeleton checkpoint to prevent senescence and premature synaptic decline. J Neuroinflammation, 22(1), 264, doi:10.1186/s12974-025-03588-z.

  5. Abu-Omar A, Bronder S, Mihm J, Schmit D, Fliser D, Sester U, Sester M, Schmidt T (2025). The Role of Cytomegalovirus-specific Immunoglobulins as Modulators of Antigen-specific T-cell Expansion In Vitro. Transplant Direct, 11(12), e1877, doi:10.1097/TXD.0000000000001877.

  6. Aljohmani A, Herr C, Witzenrath M, Pätzold L, Bischoff M, Wartenberg P, Boehm U, Beisswenger C, Tian Q, Laschke MW, Hannig M, Lehr CM, Bals R, Schilling O, Yildiz D (2025). Leukocytic ADAM10 and ADAM17 modulate disease severity and systemic outcome in bacterial and viral pneumonia. Eur Respir J, 2402060, doi:10.1183/13993003.02060-2024.

  7. Hof C, Angenendt A, Janku S, Jarzembowski L, Seelert K, Zöphel D, Hoth M, Lis A (2025). Elderly female CTLs maintain their initial activation and cytotoxicity independent of IL-2. Immun Ageing, 22(1), 52, doi:10.1186/s12979-025-00546-4.

  8. Sroka TJ, Sanwald LK, Prasai A, Hoeren J, Trivigno V, Chaumet V, Krauß LM, Weber D, Yildiz D, von der Malsburg K, Walentek P, Haberkant P, Schrul B, Feistel K, Mick DU (2025). An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems. Nat Commun, 16(1), 9691, doi:10.1038/s41467-025-65405-8.

  9. Carlein C, Hoffmann MDA, Bickelmann C, Amaral AG, Lotfinia A, de Selliers LA, Audouze-Chaud J, Wrublewsky S, Lauterbach MA, von der Malsburg K, van der Laan M, Bozem M, Hoth M, Gilon P, Ravier MA, Morgan B, Ampofo E, Higuchi T, Bertero E, Dudek J, Maack C, Roma LP (2025). Adaptive mechanisms in pancreatic islets counteract mitochondrial dysfunction in Barth syndrome. Diabetologia, doi:10.1007/s00125-025-06575-4.

  10. Aljohmani A, Yildiz D (2025). Biological sex differences in pharmacokinetics and adverse drug reactions. Naunyn Schmiedebergs Arch Pharmacol, doi:10.1007/s00210-025-04721-8.

  11. Schmitt C, Goedicke-Fritz S, Fortmann I, Zemlin M (2025). Vaccinations in preterm infants: Which and when? Semin Fetal Neonatal Med, 101670, doi:10.1016/j.siny.2025.101670.

  12. Jurastow I, Wiegand S, Rafiq A, Zakrzewicz A, Engel S, Sanna A, von der Beck D, Klepetko W, Hecker A, Günther A, Bünemann M, Krasteva-Christ G, Keshavarz M (2025). β-Nicotinamide adenine dinucleotide (β-NAD) acts as a bronchodilator. PLoS One, 20(10), e0334491, doi:10.1371/journal.pone.0334491.

  13. Bronder S, Abu-Omar A, Lennartz S, Tschausowsky D, Radun R, Fliser D, Schmidt T, Wilkens H, Schmit D, Sester M (2025). Cellular and humoral immunogenicity of respiratory syncytial virus vaccination in solid organ transplant recipients. Am J Transplant, S1600-6135(25)03003-5, doi:10.1016/j.ajt.2025.09.023.

  14. Sota A, Beck A, Wartenberg P, Gehl AL, Winter M, Wissenbach U, Freichel M, Meyer MR, Boehm U, Flockerzi V, Fecher-Trost C, Weissgerber P (2025). TRPV6 channel function is involved in endometrial epithelial cell Ca2+ signaling and female mouse fecundity. Cell Mol Life Sci, 82(1), 346, doi:10.1007/s00018-025-05857-9.

  15. Fang LP, Kirchhoff F (2025). From synaptic gatekeepers to affective-cognitive modulators: The astrocyte D1 receptor-d-serine axis in the prefrontal cortex. Acta Pharm Sin B, 15(9), 4967-4969, doi:10.1016/j.apsb.2025.08.018.

  16. Schmidt P, Pfeil U, Lafee M, Petersen S, Perniss A, Keshavarz M, Das D, Wyatt A, Boehm U, Schütz B, Kummer W, Deckmann K (2025). Tuft cells trigger neurogenic inflammation in the urethra. Cell Rep, 44(10), 116370, doi:10.1016/j.celrep.2025.116370.

  17. Fang LP, Zhao Y, Bai X (2025). Oligodendrocyte precursor cellneuronal lysosomal pathway: A novel therapeutic target for neurodegenerative diseases. Neural Regen Res, doi:10.4103/NRR.NRR-D-25-00625.

  18. Chen H, Sun YY, Li QF, Du YT, Hu NN, Sui AR, Luo XQ, Huang X, Zhu C, Yang G, Yao LL, Tang Y, Hu H, Liu CF, Tao J, Feng L, Kirchhoff F, Huang W, Li S, Ma QH (2025). Impaired macroautophagy in oligodendrocyte precursor cells suppresses neuronal plasticity via a senescence-associated signaling. Sci Adv, 11(39), eadq7665, doi:10.1126/sciadv.adq7665.

  19. Luthold C, Didion M, Rácz VS, Benedum E, Burkhart AK, Demmerle N, Wirth E, Gunaratnam G, Thangamurugan S, Helms V, Bischoff M, Ridzal A, Iden S (2025). Melanocyte differentiation and mechanosensation are differentially modulated by distinct extracellular matrix proteins. EMBO Rep, 26(21), 5270-5299, doi:10.1038/s44319-025-00583-6.

  20. Wrublewsky S, Widmann AV, Bickelmann C, Rafacho A, Roma LP, Laschke MW, Ampofo E (2025). Sex-Specific Differences in the Revascularization of Grafted Pancreatic Islets. Cells, 14(17), 1344, doi:10.3390/cells14171344.

  21. Hao W, Luo Q, Szabo IM, Gasparoni G, Tierling S, Quan W, Chang HF, Wu G, Schulze-Hentrich J, Liu Y (2025). Intestinal epithelial Dicer1 regulates gut microbiome and Alzheimer's pathology in App-knock-in mice. Alzheimers Res Ther, 17(1), 202, doi:10.1186/s13195-025-01849-w.

  22. Xu J, Mao X, Liu Z, Jiang N, Wong XE, Liu D, Wang Y, Zhan H, Liu S, Yu J, Yuan R, Bai Q, Bai X, Huang W, Xie R, Krenn V, Kirchhoff F, Wang H, Guo Z, Bian S (2025). CETN3 deficiency induces microcephaly by disrupting neural stem/progenitor cell fate through impaired centrosome assembly and RNA splicing. EMBO Mol Med, 17(10), 2735-2761, doi:10.1038/s44321-025-00302-7.

  23. Sester M, Altet-Gomez N, Andersen ÅB, Arias-Guillén M, Avsar K, Bakken Kran AM, Bothamley G, Nordholm Breschel AC, Brown J, Chesov D, Ciobanu N, Cirillo DM, Crudu V, de Souza Galvao M, Dilektasli AG, Dominguez J, Duarte R, Dyrhol-Riise AM, Goletti D, Hoffmann H, Ibraim E, Kalsdorf B, Krawczyk M, Kunst H, Lange B, Lipman M, Matteelli A, Milkiewicz P, Neyer D, Nitschke M, Oral HB, Palacios-Gutiérrez JJ, Petruccioli E, Raszeja-Wyszomirska J, Ravn P, Rupp J, Spohn HE, Toader C, Villar-Hernandez R, Wagner D, van Leth F, Martinez L, Pedersen OS, Lange C (2025). Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study. Lancet Reg Health Eur, 57, 101416, doi:10.1016/j.lanepe.2025.101416.

  24. Bortolanza M, Gobbo D, Fang L, Scheller A, Bai X, Kirchhoff F (2025). Sex-Specific Properties of Astrocytes: From Development to Evolutionary Insights. Neurochem Res, 50(4), 267, doi:10.1007/s11064-025-04512-w.

  25. Zahnow F, Jäger C, Mohamed Y, Vogelhuber G, May F, Ciocan AM, Manieri A, Maxeiner S, Krasteva-Christ G, Schnappauf O, Cobain MRD, Podsiadlowski L, Crespo-Picazo JL, García-Párraga D, Althaus M (2025). The evolutionary path of the epithelial sodium channel δ-subunit in Cetartiodactyla points to a role in sodium sensing. Commun Biol, 8(1), 1004, doi:10.1038/s42003-025-08436-7.

  26. Kardani A, Hemmer J, Diesel B, Mashayekhi V, Schomisch A, Koch M, Fecher-Trost C, Meyer MR, Ludwig N, Rishik S, Keller A, Hoppstädter J, Fuhrmann G, Kiemer AK (2025). Laminar Flow Alters EV Composition in HUVECs: A Study of Culture Medium Optimization and Molecular Profiling of Vesicle Cargo. Small Methods, 9(8), e2401841, doi:10.1002/smtd.202401841.

  27. Hellwig M, Decker J, Prates Roma L, Schunk S, Ampofo E, Rother S (2025). Sex-specific differences of advanced glycation end products in diabetes. Nutr Diabetes, 15(1), 27, doi:10.1038/s41387-025-00379-6.

  28. Das D, Boehm U (2025). A Missing Link Between Smell and Reproduction is Provided by a Novel Neuroendocrine Subsystem in the Olfactory Bulb. Endocrinology, 166(8), bqaf109, doi:10.1210/endocr/bqaf109.

  29. Rodrigues da Silva N, Gobbo D, Gomes FV, Scheller A, Kirchhoff F, Del Bel E, Silveira Guimarães F (2025). Cannabidiol reverses microglia activation and deficits of parvalbumin interneurons and their perineuronal nets in a MK-801-induced mouse model of schizophrenia. Brain Res, 1863, 149772, doi:10.1016/j.brainres.2025.149772.

  30. Lauxen JS, Vondenhoff S, Junho CVC, Martin P, Fleig S, Schütt K, Schulze-Späte U, Soehnlein O, Prates-Roma L, Döring Y, Baaten CCFMJ, Noels H (2025). Neutrophil Function in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Acta Physiol (Oxf), 241(6), e70057, doi:10.1111/apha.70057.

  31. Cunningham CE, Vizeacoumar FS, Zhang Y, Kyrylenko L, Both S, Maranda V, Dong H, Price JDW, Gao P, Wagner K, Wu Y, Lazell-Wright M, Ganapathysamy A, Hari R, Bhanumathy KK, Denomy C, Saxena A, Vizeacoumar JP, Morales AM, Khan F, Mosley S, Chen A, Katrii T, Zoller BGE, Rajamanickam K, Walke P, Gong L, Patel H, Elhasasna H, Dahiya R, Abuhussein O, Dmitriev A, Freywald T, Munhoz EP, Ruppin E, Lee JS, Rox K, Koebel M, Hopkins L, Lee CH, Yadav S, Gasparoni G, Walter J, Krishnan A, Datla R, Toosi B, Baker K, Meens J, Cescon DW, Ailles L, Leary SC, Wu Y, Empting M, Kiemer AK, Freywald A, Vizeacoumar FJ (2025). Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality. Cell Genom, 5(6), 100876, doi:10.1016/j.xgen.2025.100876.

  32. Boeckmans J, Hagström H, Cryer DR, Schattenberg JM (2025). The importance of patient engagement in the multimodal treatment of MASLD. Commun Med (Lond), 5(1), 148, doi:10.1038/s43856-025-00871-1.

  33. Renner K, Stauffenberg F, Paulus M, Neumayer S, Winter-Köhler F, Buchtler S, Schmalenberger D, Blaas S, Mohr A, Pfeifer M, Malfertheiner MV, Loew T, Sester M, Bals R, Peterhoff D, Schmidt B, Mack M (2025). Hyper-reactivity of CD8+ T cells and high expression of IL-3 correlates with occurrence and severity of Long-COVID. Clin Immunol, 277, 110502, doi:10.1016/j.clim.2025.110502.

  34. Kaesler N, Kaushik S, Frisch J, Ziegler S, Grommes J, Gombert A, Roma LP, Kuppe C, Jankowski J, Floege J, de la Puente-Secades S, Kramann R, Jankowski V (2025). Vitamin K preserves gamma-glutamyl carboxylase activity against carbamylations in uremia: Implications for vascular calcification and adjunct therapies. Acta Physiol (Oxf), 241(5), e70040, doi:10.1111/apha.70040.

  35. Dancker TA, Elhawy MI, Rittershauß R, Tian Q, Schwarz Y, Hoffmann MDA, Carlein C, Wyatt A, Wahl V, Speyerer D, Kandah A, Boehm U, Prates Roma L, Bruns D, Lipp P, Krasteva-Christ G, Lauterbach MA (2025). Functional Microendoscopy Reveals Calcium Responses of Single Cells in Tracheal Tuft Cells and Kidney Podocytes. Small, 21(21), e2411341, doi:10.1002/smll.202411341.

  36. Thiemann M, Zimmermann M, Diederich C, Zhan H, Lebedev M, Pletz J, Baumgarten J, Handke M, Müsken M, Breinbauer R, Krasteva-Christ G, Zanin E, Empting M, Schiedel M, Kunick C, Blankenfeldt W (2025). From Bones to Bugs: Structure-Based Development of Raloxifene-Derived Pathoblockers That Inhibit Pyocyanin Production in Pseudomonas aeruginosa. J Med Chem, 68(7), 7390-7420, doi:10.1021/acs.jmedchem.4c03065.

  37. Maxeiner S, Walter L, Zeitz SL, Krasteva-Christ G (2025). Comprehensive Analysis of Rodent-Specific Probasin Gene Reveals Its Evolutionary Origin in Pseudoautosomal Region and Provides Novel Insights into Rodent Phylogeny. Biology (Basel), 14(3), 239, doi:10.3390/biology14030239.

  38. Gobbo D, Kirchhoff F (2025). Animal-based approaches to understanding neuroglia physiology in vitro and in vivo. Handb Clin Neurol, 209, 229-263, doi:10.1016/B978-0-443-19104-6.00012-7.

  39. Feng X, Andersson T, Flüchter P, Gschwend J, Berest I, Muff JL, Lechner A, Gondrand A, Westermann P, Brander N, Carchidi D, De Tenorio JC, Pan T, Boehm U, Klose CSN, Artis D, Messner CB, Leinders-Zufall T, Zufall F, Schneider C (2025). Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypoproliferation. Nat Immunol, 26(4), 567-581, doi:10.1038/s41590-025-02104-y.

  40. Lange C, Bothamley G, Günther G, Guglielmetti L, Kontsevaya I, Kuksa L, Lange B, Lorent N, Saluzzo F, Sester M, Tebruegge M, Tunesi S, Tweed C, Tuberculosis Network European Trials group (TBnet) (2025). A Year in Review on Tuberculosis and Non-tuberculous Mycobacteria Disease: A 2025 Update for Clinicians and Scientists. Pathog Immun, 10(2), 1-45, doi:10.20411/pai.v10i2.791.

  41. Abu-Omar A, Mihm J, Bronder S, Schmidt T, Sester M, Sester U (2025). CMV management of patients with leukopenia after CMV high-risk kidney transplantation. Transpl Immunol, 89, 102188, doi:10.1016/j.trim.2025.102188.

  42. Fang LP, Lin CH, Medlej Y, Zhao R, Chang HF, Guo Q, Wu Z, Su Y, Zhao N, Gobbo D, Wyatt A, Wahl V, Fiore F, Tu SM, Boehm U, Huang W, Bian S, Agarwal A, Lauterbach MA, Yi C, Niu J, Scheller A, Kirchhoff F, Bai X (2025). Oligodendrocyte precursor cells facilitate neuronal lysosome release. Nat Commun, 16(1), 1175, doi:10.1038/s41467-025-56484-8.

  43. Godeanu S, Mușat MI, Scheller A, Osiac E, Cătălin B (2025). Minimal differences observed when comparing the morphological profiling of microglia obtained by confocal laser scanning and optical sectioning microscopy. Front Neuroanat, 18, 1507140, doi:10.3389/fnana.2024.1507140.

  44. Abdel Wadood N, Hollenhorst MI, Elhawy MI, Zhao N, Englisch C, Evers SB, Sabachvili M, Maxeiner S, Wyatt A, Herr C, Burkhart AK, Krause E, Yildiz D, Beckmann A, Kusumakshi S, Riethmacher D, Bischoff M, Iden S, Becker SL, Canning BJ, Flockerzi V, Gudermann T, Chubanov V, Bals R, Meier C, Boehm U, Krasteva-Christ G (2025). Tracheal tuft cells release ATP and link innate to adaptive immunity in pneumonia. Nat Commun, 16(1), 584, doi:10.1038/s41467-025-55936-5.