Guha, Somraj

Dr. Somraj Guha

Gebäude C4 2, Labor E.01
Tel.: +49 681 302-2736



Synthese von Cyclopeptiden


12   F. E. Morreale, S. Kleine, J. Leodolter, S. Junker, D. M. Hoi, S. Ovchinnikov, A. Okun, J. Kley, R. Kurzbauer, L. Junk, S. Guha, D. Podlesainski, U. Kazmaier, G. Boehmelt, H. Weinstabl, K. Rumpel, V. M. Schmiedel, M. Hartl, D. Haselbach, A. Meinhart, M. Kaiser, T. Clausen, "BacPROTACs mediate targeted protein degradation in bacteria", Cell 2022, 185, 2203-2205. DOI: 10.1016/j.cell.2022.05.009.

11   S. Guha, I. Kazi, C. H. Suresh, G. Sekar, "Iodine-promoted controlled and selective oxidation of (aryl)(heteroaryl)methanes", J. Org. Chem202287, 5424–5429.

10   A. Nandy, I. Kazi, S. Guha, G. Sekar, "Visible Light Driven Halogen Bond–Assisted Direct Synthesis of Heteroaryl Thioethers using Metal–Free One–Pot C–I Bond Formation/C–S Cross Coupling Reaction",  J. Org. Chem202186, 2570–2581.

9   S. Guha,  S. Senthilkumar, E., Voss, L. F., Tietze, "Aldosterone Glucuronide, an Important Biomarker: Synthesis and Structure Elucidation of Novel Isomers", Chem. Eur. J. 202026, 15733–15737.

8   N. Sundarvelu, S.Guha, G. Sekar, "Iodonium Ion-Catalyzed Domino Synthesis of Z-Selective α,β-Diphenylthio Enones from Easily Accessible Secondary Alcohols", J. Org. Chem. 2020, 85, 5895.

7   R. Prasanna, S.Guha, G. Sekar, "Chemoselective Reduction of α,β-Unsaturated Carbonyl Compound using Potassium Ethyl Xanthate via Proton Coupled Electron Transfer", Org. Lett. 2019, 21, 2650.

6   I. Kazi, S.Guha, G. Sekar, "Halogen Bond–Assisted Electron–Catalyzed Atom Economic Iodination of Heteroarenes Under Mild Reaction Condition", J. Org. Chem. 2019, 84, 11, 6642.

5   S. Guha, G. Sekar, "Metal–free Halogen(I) Catalysts for Oxidation of (Aryl)(heteroaryl)methanes to Ketones or Esters: Selectivity Control by Halogen Bond", Chem. Eur. J. 2018, 24, 14171.

4   S. Guha, I. Kazi, P. Mukherjee, G. Sekar, "Halogen–bonded Iodonium Ion Catalysis: A Route to α–Hydroxy Ketone via Domino Oxidations of Secondary Alcohol and Aliphatic C–H Bond with High Selectivity and Control", Chem. Commun. 2017, 53, 10942.

3   S. Guha, I. Kazi, A. Nandy, G. Sekar, "Role of Lewis-Base-Coordinated Halogen(I) Intermediates in Organic Synthesis: The Journey from Unstable Intermediates to Versatile Reagents", Eur. J. Org. Chem. 2017, 2017, 5497. (Invited Review Article, Cover page, Highlighted in ‘Outstanding Organics’)

2   I. Kazi, S.Guha, G. Sekar, "CBr4 as a Halogen Bond Donor Catalyst for the Selective Activation of Benzaldehydes to Synthesize α, β-Unsaturated Ketones", Org. Lett. 2017, 19, 1244. (Highlighted in Organic Chemistry Portal)

1   S. Guha, V. Rajeshkumar, S. S. Kotha, G. Sekar, "A Versatile and One Pot Strategy to Synthesize α-Amino Ketone from Benzylic Secondary Alcohol Using N-bromosuccinamide", Org. Lett. 2015, 17, 406. (Highlighted in Organic Chemistry Portal).