Junk, Lukas

Lukas Junk

Gebäude C4 2, Labor E.01
Tel.: +49 681 302-2736
E-Mail

 

Arbeitsgebiet

Synthese von Cyclopeptiden

Publikationen

12   F. E. Morreale, S. Kleine, J. Leodolter, S. Junker, D. M. Hoi, S. Ovchinnikov, A. Okun, J. Kley, R. Kurzbauer, L. Junk, S. Guha, D. Podlesainski, U. Kazmaier, G. Boehmelt, H. Weinstabl, K. Rumpel, V. M. Schmiedel, M. Hartl, D. Haselbach, A. Meinhart, M. Kaiser, T. Clausen, "BacPROTACs mediate targeted protein degradation in bacteria", Cell 2022, in press. DOI: 10.1016/j.cell.2022.05.009.

11   L. Junk, A. Ullrich, U. Kazmaier, "Synthesis of Modified Tryptophan Derivatives" in Targets in Heterocyclic Systems - Chemistry and Properties (Hrsg.: O. A. Attanasi, B. Gabriele, P. Merino, D. Spinelli), Italian Chemical Society, 202225, 342-364.

10   A. Ullrich, L. Junk, U. Kazmaier, "Three Methods for the Solution Phase Synthesis of Cyclic Peptides" in Methods in Molecular Biology - Peptide Macrocycles (Hrsg.: M. B. Coppock , A. J. Winton), Humana, New York, NY, 2022, 2371, 43-61. https://doi.org/10.1007/978-1-0716-1689-5_4.

9   U. Kazmaier, L. Junk, "The Synthesis of Ilamycins/Rufomycins and Cyclomarins, Marine Cyclopeptides that Demonstrate anti-Malaria and anti-Tuberculosis Activity", Mar. Drugs 2021, 19, 446. DOI: 10.3390/md19080446.

8   L. Junk, E. Papadopoulos, U. Kazmaier, "Tryptophan N1-Alkylation: Quick and Simple Access to Diversely Substituted Tryptophans", Synthesis 2021, 53, 2503–2511. DOI: 10.1055/a-1404-5079.

7   L. Junk, U. Kazmaier, "The Allylic Alkylation of Ketone Enolates", ChemistryOpen 2020, 9, 929–952. DOI: 10.1002/open.202000175.

6   P. Servatius, L. Junk, U. Kazmaier, "Peptide Modifications, Versatile Tools in Peptide and Natural Product Syntheses", Synlett 2019, 30, 1289-1302, DOI: 10.1055/s-0037-1612417, DOI: 10.1055/s-0037-1612417.

5   L. Junk, U. Kazmaier, "Total Synthesis and Configurational Revision of Mozamide A – a Hydroxy-Brunsvicamide", J. Org. Chem.  2019, 84, 2489–2500, DOI: 10.1021/acs.joc.8b02836.

4   L. Junk, U. Kazmaier, "Totalsynthese und Konfigurationsrevision der Keramamide A und L aus gemeinsamer Vorstufe via späte Indolsynthese", Angew. Chem. 2018, 130, 11602−11606; Angew. Chem. Int. Ed. 2018, 57, 11432−11435; doi: 10.1002/ange.201806657.

3   L. Junk, U. Kazmaier, "Synthesis of Indoles and Tryptophan Derivatives via Photoinduced Nitrene C-H Insertion", Org. Biomol. Chem.  2016, 14, 2916−2923.

2   L. Junk, U. Kazmaier, "A straightforward protocol for the synthesis of functionalized tryptophan peptides via Stille coupling, azidation and photoinduced nitrene insertion", Synlett  2016, 1531-1536.

1   J. Hoffmann, J. Gorges, L. Junk, U. Kazmaier, "Synthesis of Pretubulysin-Derivatives via the TubUgi-Approach", Org. Biomol. Chem.  2015, 13, 6010–6020.