Publications

2021
Wachten, D., Mick, D.U. (2021)
Signal transduction in primary cilia - analyzing and manipulating GPCR and second messenger signaling.
Pharmacol. Ther., Online ahead of print doi: 10.1016/j.pharmthera.2021.107836.

May, E.A., Kalocsay, M., Galtier D'Auriac I., Schuster P.S., Gygi SP, Nachury M.V., Mick, D.U. (2021) 
Time-resolved proteomics profiling of the ciliary Hedgehog response.
J. Cell. Biol. 220, e202007207, doi: 10.1083/jcb.202007207.

May, E.A., Sroka, T.J., Mick, D.U. (2021)
Phosphorylation and ubiquitylation regulate protein trafficking, signaling, and the biogenesis of primary cilia.
Front. Cell. Dev. Biol. 9, 664279, doi: 10.3389/fcell.2021.664279.

2020
Hansen, J-N., Kaiser, F., Klausen, C., Stüven, B., Chong, R., Bönigk, W., Mick, D.U., Möglich, A., Jurisch-Yaksi, N.,  Schmidt, F.I., Wachten, D. (2020)
Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium.
Elife 9:e57907, doi: 10.7554/eLife.57907

2019
Mick, D.U. (2019)
Establishing cell culture-based experimental setups for proximity labeling using ascorbate peroxidase (APEX).
Methods Mol. Biol. 2008, 29-39.

Nachury, M.V. and Mick, D.U. (2019)
Establishing and regulating the composition of cilia for signal transduction.
Nat. Rev. Mol. Cell Biol. 20, 389-405. doi: 10.1038/s41580-019-0116-4.

2016
Bareth, B., Nikolov, M., Lorenzi, I., Hildenbeutel, M., Mick, D. U., Helbig, C., Urlaub, H., Ott, M., Rehling, P. and Dennerlein, S. (2016)
Oms1 associates with cytochrome c oxidase assembly intermediates to stabilize newly synthesized Cox1.
Mol. Cell. Biol. 27, 1570-1580.

2015
Mick, D. U., Rodrigues, R. B., Leib, R. D., Adams, C. M., Chien, A. S., Gygi, S. P., and Nachury, M. V. (2015)
Proteomics of Primary Cilia by Proximity Labeling.
Dev. Cell 35, 497-512.
Commented by Nikonova, A. S. and Golemis, E. A. in the same issue

2013
Bareth, B., Dennerlein, S., Mick, D. U., Nikolov, M., Urlaub, H. and Rehling, P. (2013)
The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation.
Mol. Cell. Biol., 33, 4128-4137.

2012
Mick, D. U.*, Dennerlein, S.*, Wiese, H., Reinhold, R., Pacheu-Grau, D., Lorenzi, I., Sasarman, F., Weraarpachai, W., Shoubridge, E. A., Warscheid, B. and Rehling, P. (2012)
MITRAC links mitochondrial protein translocation to respiratory chain assembly and translational regulation.
Cell 151, 1528-1541.
*authors contributed equally to this work

2011
Reinhold, R., Bareth, B., Balleininger, M., Wissel, M., Rehling, P. and Mick, D. U. (2011)
Mimicking a SURF1 allele reveals uncoupling of cytochrome c oxidase assembly from translational regulation in yeast.
Hum. Mol. Genet. 20, 2379-2393.

 
Lupo, D., Vollmer, C., Deckers, M., Mick, D. U., Tews, I., Sinning, I. and Rehling, P. (2011)
Mdm38 is a 14-3-3-like receptor and associates with the protein synthesis machinery at the inner mitochondrial membrane.
Traffic 12, 1457-1466.

2010
Mick, D. U., Vukotic, M., Piechura, H., Meyer, H. E., Warscheid, B., Deckers, M. and Rehling, P. (2010)
Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria.
J. Cell Biol. 191, 141-154.

 
Chacinska, A., van der Laan, M., Mehnert, C. S., Guiard, B., Mick, D. U., Hutu, D. P., Truscott, K. N., Wiedemann, N., Meisinger, C., Pfanner, N., and Rehling, P. (2010)
Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting.
Mol. Cell. Biol. 30, 307-318.

Bauerschmitt, H.*, Mick, D. U.*, Deckers, M., Vollmer C., Funes S., Kehrein K., Ott M., Rehling P. and Herrmann, J. M. (2010)
Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation.
Mol. Cell. Biol. 21, 1937-1944.
*authors contributed equally to this work

2007
Mick, D. U., Wagner, K., van der Laan, M., Frazier, A. E., Perschil, I., Pawlas, M., Meyer, H. E., Warscheid, B., and Rehling, P. (2007)
Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly.
EMBO J. 26, 4347-4358.

2006
Meinecke, M., Wagner, R., Kovermann, P., Guiard, B., Mick, D. U., Hutu, D. P., Voos, W., Truscott, K. N., Chacinska, A., Pfanner, N., Rehling, P. (2006)
Tim50 maintains the permeability barrier of the mitochondrial inner membrane.
Science 312, 1523-1526.

Frazier, A. E., Taylor, R. D., Mick, D. U., Warscheid, B., Stoepel, N., Meyer, H. E., Ryan, M. T., Guiard, B., and Rehling, P. (2006)
Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery.
J. Cell Biol. 172, 553-564.

Van der Laan, M., Wiedemann, N., Mick, D. U., Guiard, B., Rehling, P, Pfanner, N. (2006)
A role for Tim21 in membrane potential-dependent preprotein sorting in mitochondria.
Curr. Biol. 16, 2271-2276.

2005
Brandner, K., Mick, D. U., Frazier, A.E., Taylor, R. D., Meisinger, C., and Rehling, P. (2005)
Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome.
Mol. Biol. Cell 16, 5202-5214.

 
Reviews
Mick, D. U., Fox, T. D. and Rehling, P. (2011)
Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation.
Nat. Rev. Mol. Cell Biol. 12, 14-20.

Wagner, K., Mick, D. U., and Rehling, P. (2009)
Protein transport machineries for precursor translocation across the inner mitochondrial membrane.
Biochim. Biophys. Acta 1793, 52-59.