Epigenetic changes play an important role in complex human diseases such as cancer. In our research we apply NGS based sequencing technologies and ultra-deep sequencing to identify novel highly sensitive epigenetic markers in colon cancer that can be used to allow
i) high sensitive non-invasive early diagnosis of cancer cells in body fluids,
ii) a better differentiation between individual tumor types and
iii) to define a more rational basis for therapeutical intervention.