Publikationsliste 2020-2016


244   L. Junk, U. Kazmaier, "The Allylic Alkylation of Ketone Enolates", ChemistryOpen 2020, 9, 929–952. DOI: 10.1002/open.202000175.

243   P. Chitirala, K. Ravichandran, C. Schirra, H.-F. Chang, E. Krause, U. Kazmaier, M. A. Lauterbach, J. Rettig, "Role of V-ATPase a3-Subunit in Mouse CTL Function", J. Immunol. 2020, DOI: 10.4049/jimmunol.1901536.

242   C. Prudel, K. Huwig, U. Kazmaier, “Stereoselective Allylic Alkylations of Amino Ketones and their Application in the Synthesis of Highly Functionalized Piperidines”, Chem. Eur. J. 2020, 26, 3181–3188, DOI: 10.1002/chem.202000051.


241   I. Truebenbach, W. Zhang, Y. Wang, S. Kern, M. Höhn, S. Reinhard, J. Gorges, U. Kazmaier, E. Wagner, "Co-delivery of pretubulysin and siEG5 to EGFR 2 overexpressing carcinoma cells", Int. J. Pharm. 2019, DOI: 10.1016/j.ijpharm.2019.118570.

240   S. Wang, A. Crevenna, I. Ugur, A. Marion, I. Antes, U. Kazmaier, M. Hoyer, D. Lamb, F. Gegenfurtner, Z. Kliesmete, C. Ziegenhain, W. Enard, A. Vollmar, S. Zahler, "Actin stabilizing compounds show specific biological effects due to their binding mode", Sci. Rep. 2019, 9, 9731, DOI: 10.1038/s41598-019-46282-w.

239   A. Horn, U. Kazmaier, "Stereoselective Modification of “α-Hydroxyacid Dipeptides” by Palladium Catalyzed Allylic Alkylation", Org. Lett. 2019, 21, 4595-4599, DOI: 10.1021/acs.orglett.9b01497.

238   T. Kinsinger, U. Kazmaier, "Mono-selective β-C–H arylation of N-methylated amino acids and peptides promoted by 2-(methylthio)aniline directing group", Org. Biomol. Chem. 2019, 17, 5595-5600, DOI: 10.1039/C9OB00966C.

237   I. Truebenbach, S. Kern, D. Loy, J. Gorges, U. Kazmaier, E. Wagner, "Combination chemotherapy of L1210 tumors in mice with pretubulysin and methotrexate nanomicelles", Mol. Pharmaceut. 2019, 16, 2405-2417, DOI: 10.1021/acs.molpharmaceut.9b00038.

236   A. Kiefer, C. D. Bader, J. Held, A. Esser, J. Rybniker, M. Empting, R. Müller, U. Kazmaier, "Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Myco­bacterium Tuberculosis and Plasmodium Falsiparum", Chem. Eur. J. 2019, 25, 8894-8902, DOI: 10.1002/chem.201901640.

235   P. Servatius, T. Stach, U. Kazmaier, "Total synthesis of luminmycin A, a cryptic natural product from Photorhabdus luminescens", Eur. J. Org. Chem. 2019, 3163-3168, DOI: 10.1002/ejoc.201900460.

234   M. Kohr, U. Kazmaier, "Halogenated allyl alcohol derivatives – versatile dielectrophiles for palladium-catalyzed allylic alkylations", Eur. J. Org. Chem. 2019, 2843–2849, DOI: 10.1002/ejoc.201900310.

233   P. Servatius, L. Junk, U. Kazmaier, "Peptide Modifications, Versatile Tools in Peptide and Natural Product Syntheses", Synlett 2019, 30, 1289-1302, DOI: 10.1055/s-0037-1612417.

232   T. Dubich, A. Lieske, S. Santag, G. Beauclair, J. Rückert, J. Herrmann, J. Gorges, G. Bäsche, U. Kazmaier, H. Hauser, M. Stadler, T. F. Schulz, D. Wirth, "An endothelial cell line infected by Kaposi's sarcoma-associated herpes virus (KSHV) allows the investigation of Kaposi's sarcoma and the validation of novel viral inhibitors in vitro and in vivo", J. Mol. Med. 2019, 97, 311–324, DOI: 10.1007/s00109-018-01733-1.

231   S. Kern, I. Trübenbach, M. Höhn, J. Gorges, U. Kazmaier, S. Zahler, A. M. Vollmar, E. Wagner, "Combined Antitumoral Effects of Pretubulysin and Methotrexate", Pharmacol. Res. Persp. 2019, e00460, DOI: 10.1002/prp2.460.

230   L. Junk, U. Kazmaier, "Total Synthesis and Configurational Revision of Mozamide A – a Hydroxy-Brunsvicamide", J. Org. Chem. 2019, 84, 2489–2500, DOI: 10.1021/acs.joc.8b02836.

229   F. Koczian, O. Naglo, J. Vomacka, B. Vick, P. Servatius, T. Zisis, B. Hettich, U. Kazmaier, S. A. Sieber, I. Jeremias, S. Zahler, S. Braig, "Targeting the ER-Mitochondria Interface Sensitizes Leukemia Cells Towards Cytostatics", Haematologica 2018, DOI: 10.3324/haematol.2018.197368.

228   A. Kiefer, U. Kazmaier, "Syntheses of Cyclomarins – Interesting Marine Natural Products with Distinct Mode of Action towards Malaria and Tuberculosis", Synthesis 2019, 51, 107–121, DOI: 10.1055/s-0037-1610377.

227   A. Kiefer, U. Kazmaier, "Synthesis of modified β-methoxyphenylalanines via diazonium chemistry and their incorporation in desoxycyclomarin analogues", Org. Biomol. Chem. 2019, 17, 88–102, DOI: 10.1039/C8Ob02777C.


226   T. Kinsinger, U. Kazmaier, "C-H-Functionalization of N-Methylated Amino Acids and Peptides as Tool in Natural Product Synthesis – Synthesis of Abyssenine A and Mucronine E", Org. Lett. 2018, 20, 7726–7730.

225   S. Kappler, L. Karmann, C. Prudel, J. Herrmann, G. Caddeu, R. Müller, A. M. Vollmar, S. Zahler, U. Kazmaier, "Synthesis and biological evaluation of (modified) miuraenamides", Eur. J. Org. Chem. 2018, 6952–6965.

224   F. A. Gegenfurtner, T. Zisis, N. Al Danaf, W. Schrimpf, Z. Kliesmete, C. Ziegenhain, W. Enard, U. Kazmaier, D. C. Lamb, A. M. Vollmar, S. Zahler, "Transcriptional effects of actin binding compounds: the cytoplasm sets the tone", Cell. Mol. Life Sci. 2018, 75, 4539–4555.

223   J. Gorges, L. Kjaerulff, F. Panter, T. Hoffmann, U. Kazmaier, R. Müller, "Structure, total synthesis and biosynthesis of Chloromyxamides – myxobacterial tetrapeptides featuring an uncommon 6-chloromethyl-5-methoxypipecolic acid building block", Angew. Chem. 2018, 130,14466–14471; Angew.Chem.Int.Ed. 2018, 57,14270–14275.

222   P. Servatius, U. Kazmaier, "Total Synthesis of Trapoxin A, a fungal HDAC-inhibitor from Helicoma ambiens", J. Org. Chem. 2018, 83, 11341−11349.

221   L. Junk, U. Kazmaier, "Totalsynthese und Konfigurationsrevision der Keramamide A und L aus gemeinsamer Vorstufe via späte Indolsynthese", Angew. Chem. 2018, 130, 11602−11606; Angew. Chem. Int. Ed. 2018, 57, 11432−11435.

220   M. Kohr, U. Kazmaier, "Stereoselective synthesis of d4-(S)-lysine from (S)-serine", Synthesis 2018, 50, 4690–4694.

219   P. M. Klein, S. Kern, D.-J. Lee, J. Schmaus, J. Gorges, U. Kazmaier, E. Wagner, "Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo", Biomaterials 2018178, 630−642.

218   K. Weinhäupl, J. Lelievre, A. Goldberg, U. Kazmaier, P. Schanda, H. Fraga, "The natural antibiotic Cyclomarin blocks Arginine-Phosphate induced dynamics in ClpC1 N-terminal domain – A possible mechanism of drug action", J. Biol. Chem. 2018, 293, 8379−8393.

217   J. Gorges, U. Kazmaier, "Matteson Homologation-based Total Synthesis of Lagunamide A", Org. Lett.  2018, 20, 2033−2036.

216   P. Servatius, U. Kazmaier, "Total synthesis of the natural HDAC inhibitor Cyl-1", Org. Biomol. Chem. 2018, 16, 3464–3472.

215   A. Horn, U. Kazmaier, "Purified mCPBA, a useful reagent for the oxidation of aldehydes", Eur. J. Org. Chem. 2018, 2531–2536.


214   C. Moser, D. Rüdiger, F. Förster, J. von Blume, P. Yu, B. Küster, U. Kazmaier, A. M. Vollmar, S. Zahler, "Persistent inhibition of cell migration by sub-toxic doses of miuraenamide, an actin nucleator", Sci. Rep. 2017, 7, 16407; DOI: 10.1038/s41598-017-16759-7.

213   R. Schwenk, T. Stehning, I. Bischoff, A. Ullrich, U. Kazmaier, R. Fürst, "The anti-metastatic action of the microtubule-targeting agent pretubulysin is associated with the trapping of tumor cells to the endothelium", Oncotarget 2017, 77622-77633.

212   U. Kazmaier, T. Doroshenko, K. Bauer, I. Filbrich, A. Grueter, G. Jung, A. Ullrich, "Coumaryl triflates, versatile building blocks for the modification of coumarins and for fluorescence labelling", Synthesis 2017, 49, 2743-2748.

211   I. Trübenbach, J. Gorges, J. Kuhn, E. Baratti, U. Kazmaier, E. Wagner, U. Lächelt, "Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy", Macromol. Biosci. 2017, DOI: 10.1002/mabi.201600520.


210   B. Mondal, B. Roy, U. Kazmaier, "Stereoselective Peptide Modifications via b-C(sp3)-H Arylations", J. Org. Chem. 2016, 81, 11646-11655.

209   U. Kazmaier, "Non-stabilized enolates - versatile nucleophiles in transition-metal-catalysed allylic alkylations", Org. Chem. Front. 2016, 3, 1541-1560.

208   L. Schmidt, T. Doroshenko, P. Barbie, A. Grueter, G. Jung, U. Kazmaier, "Synthesis of fluorogenic amino acids via Pd-catalyzed allylic alkylations", Synthesis 2016, 3077-3086.

207   P. Barbie, U. Kazmaier, "Total synthesis of desoxycyclomarin C and the cyclomarazines A and B", Org. Biomol. Chem. 2016, 14, 6055−6064.

206   P. Barbie, U. Kazmaier, "Total synthesis of cyclomarins A, C and D, marine cyclopeptides with interesting anti tuberculosis and anti malaria activitites", Org. Biomol. Chem. 2016, 14, 6036−6054.

205   C. K Maurer, M. Fruth, M. Empting, O. Avrutina, J. Hoßmann, S. Nadmid, J. Gorges, J. Herrmann, U. Kazmaier, P. Dersch, R. Müller, R. W Hartmann, "Discovery of the first small molecule CsrA-RNA interaction inhibitors using biophysical screening technologies", Future Med. Chem. 2016, 8, 931-947.

204   L. Junk, U. Kazmaier, "A straightforward protocol for the synthesis of functionalized tryptophan peptides via Stille coupling, azidation and photoinduced nitrene insertion", Synlett 2016, 1531-1536.

203   L. Junk, U. Kazmaier, "Synthesis of Indoles and Tryptophan Derivatives via Photoinduced Nitrene C-H Insertion", Org. Biomol. Chem. 2016, 14, 2916−2923.

202   P. Barbie, U. Kazmaier, "Total Synthesis of Cyclomarin A, a Marine Cycloheptapeptide with anti-Tuberculosis and anti-Malaria Activity", Org. Lett. 2016, 18, 204−207.