2023-2021

Publikationsliste 2023-2021

2023

278   M. Tost, U. Kazmaier, "Stereoselective Synthesis of Secondary and Tertiary Boronic Esters via Matteson Homologation", Org. Lett. 2023, 25, 6835–6839. DOI: 10.1021/acs.orglett.3c02360

277  T. F. Primke, R. Ingelfinger, M. A. F. Elewa, I. Macinkovic, A. Weigert, M. P. Fabritius, C. A. Reichel, A. Ullrich, U. Kazmaier, L. D. Burgers, R. Fürst, " The Microtubule-Targeting Agent Pretubulysin Impairs the Inflammatory Response in Endothelial Cells by a JNK-Dependent Deregulation of the Histone Acetyltransferase Brd4", Cells 2023, 12, 2112. DOI: 10.3390/cells12162112

276   M. Kohr, U. Kazmaier, "Synthesis of HC-Toxin via Matteson Homologation and C-H-Functionalization", J. Org. Chem. 2023, 88, 10869–10880. DOI: 10.1021/acs.joc.3c00914

275   M. Kohr, N. Papenkordt, M. Jung, U. Kazmaier, "Total synthesis and biological evaluation of histone deacetylase inhibitor WF-3161", Org. Biomol. Chem. 2023, 21, 4382−4387. DOI: 10.1039/D3OB00641G.

274   K. Bauer, U. Kazmaier, "First Total Synthesis of Thiamyxins A-C and Thiamyxin E, a Potent Class of RNA-Virus Inhibiting (Cyclo)depsipeptides", Angew. Chem.2023, 135, 202305445. DOI: 10.1002/anie.202305445.

273   T. Kinsinger, U. Kazmaier, "Stereoselective synthesis of five- and six-membered carbocycles via Matteson homologation / ring closing metathesis", Org. Chem. Front. 2023, 10, 2963−2967. DOI: 10.1039/D3QO00457K.

272   T. Kinsinger, P. L. Schäfer, U. Kazmaier, "Stereoselective Synthesis of Highly Substituted O-Heterocycles via Matteson Homologation: a Ring-Closing Metathesis Approach", Org. Lett. 2023, 25, 3303–3307. DOI: 10.1021/acs.orglett.3c01099.

271   R. Priester, U. Kazmaier, "A Straightforward Synthesis of Emericellamide A using Matteson’s Homologation Approach", Synlett 2023, in press. DOI: 10.1055/a-2077-2113.

270   D. M. Hoi, S. Junker, L. Junk, K. Fischel, D. Podlesainski, K. Schwechel, F. Kasani, L. van Geelen, J. Leodolter, P. Hawkins, F. E. Morreale, S. Kleine, S. Guha, K. Rumpel, V. M. Schmiedel, H. Weinstabl, A. Meinhart, R. Kalscheuer, R. J. Payne, M. Kaiser, M. Hartl, G. Boehmelt, U. Kazmaier, T. Clausen, "Development of a dual Clp-targeting BacPROTAC that impairs mycobacterial proteostasis and survival", Cell 2023, 186, 2176–2192. DOI: 10.1016/j.cell.2023.04.009.

2022

269   T. Kinsinger, U. Kazmaier, "Combining Matteson Homologations and Claisen Rearrange­ments - An Efficient Tool for Amino Acid Synthesis",  Eur. J. Org. Chem. 2022, e202201345. DOI: 10.1002/ejoc.202201345.

268   M. Kohr, C. Walt, J. Dastbaz, R. Müller, U. Kazmaier, "Total Synthesis of Myxoprincomid, a secondary metabolite from Myxococcus xanthus", Org. Biomol. Chem. 2022, 20, 9609–9612. DOI: 10.1039/D2OB02021A .

267   J. Greve, A. Mogk, U. Kazmaier, "Total Synthesis and Biological Evaluation of Modified Ilamycin Derivatives", Mar. Drugs 2022, 20, 632. DOI: 10.3390/md20100632.

266   A. Horn, U. Kazmaier, "Stereoselective Synthesis of the Sidechain of Callipeltin A", Org. Lett. 2022, 24, 7072–7076. DOI: 10.1021/acs.orglett.2c02586.

265   A. Horn, U. Kazmaier, "Synthesis of the Cyclic Heptapeptide Core of Callipeltin A", Org. Chem. Front. 2022, 9, 5213−5218. DOI: 10.1039/D2QO01120D.

264   T. Kinsinger, U. Kazmaier, "Matteson Homologation of Arylboronic Esters", Eur. J. Org. Chem. 2022, e202200625. DOI: 10.1002/ejoc.202200625.

263   C. Baltes, D. Thalla, U. Kazmaier, F. Lautenschläger, "Stabilizing actin inhibits single cell migration", Front. Cell Dev. Biol. 2022, 10931880. DOI: 10.3389/fcell.2022.931880.

262   F. E. Morreale, S. Kleine, J. Leodolter, S. Junker, D. M. Hoi, S. Ovchinnikov, A. Okun, J. Kley, R. Kurzbauer, L. Junk, S. Guha, D. Podlesainski, U. Kazmaier, G. Boehmelt, H. Weinstabl, K. Rumpel, V. M. Schmiedel, M. Hartl, D. Haselbach, A. Meinhart, M. Kaiser, T. Clausen, "BacPROTACs mediate targeted protein degradation in bacteria", Cell 2022, 185, 2203-2205. DOI: 10.1016/j.cell.2022.05.009.

261   T. Kinsinger, U. Kazmaier, "Application of Vinyl Nucleophiles in Matteson Homologations", Org. Lett. 2022, 24, 3599−3603. DOI: 10.1021/acs.orglett.2c01119.

260   O. Andler, U. Kazmaier, "Stereoselective Synthesis of a Protected Side Chain of Meliponamycin A", Org. Lett. 2022, 24, 2541−2545. DOI: 10.1021/acs.orglett.2c00701.

259   N. Neis, F. Xie, D. Krug, H. Zhao, A. Siebert, T. Binz, C. Fu, R. Müller, U. Kazmaier, "Stereoselective Syntheses of Deuterated Pipecolic Acids as Tools to Investigate the Stereoselectivity of the Hydroxylase GetF", Eur. J. Org. Chem. 2022, e202200162. DOI: 10.1002/ejoc.202200162.

258   V. Jakob, B. G. E. Zoller, J. Rinkes, Y. Wu, A. F. Kiefer, M. Hust, S. Helmsing, A. M. White, P. J. Harvey, T. Durek, D. J. Craik, A. Siebert, U. Kazmaier, M. Empting, "Phage Display-based Discovery of Cyclic Peptides against the Broad Spectrum Bacterial Anti-Virulence Target CsrA", Eur. J. Med. Chem. 2022, 231, 114148. DOI: 10.1016/j.ejmech.2022.114148.

257   P. Servatius, U. Kazmaier, "Synthesis and late stage modifications of Cyl-derivatives", Beilstein J. Org. Chem. 2022, 18, 174–181. DOI: 10.3762/bjoc.18.19.

2021

256   M. Tost, O. Andler, U. Kazmaier, "A Matteson homologation-based synthesis of doliculide and derivatives", Eur. J. Org. Chem. 2021, 6459–6471. DOI: 10.1002/ejoc.202101345.

255   O. Andler, U. Kazmaier, "Application of Allylzinc Reagents as Nucleophiles in Matteson Homologations", Org. Lett. 2021, 23, 8439–8444. DOI: 10.1021/acs.orglett.1c03164.

254   S. Wang, M. Meixner, L. Yu, L. Karmann, U. Kazmaier, A. M. Vollmar, I. Antes, S. Zahler, "Turning the Actin Nucleating Compound Miuraenamide into Nucleation Inhibitors", ACS Omega 2021, 6, 22165–22172. DOI: 10.1021/acsomega.1c02838.

253   L. Franz, U. Kazmaier, A. W. Truman, J. Koehnke, "Bottromycins - Biosynthesis, Synthesis and Activity", Nat. Prod. Rep. 2021, 38, 1659–1683. DOI: 10.1039/d0np00097c.

252   U. Kazmaier, L. Junk, "The Synthesis of Ilamycins/Rufomycins and Cyclomarins, Marine Cyclopeptides that Demonstrate anti-Malaria and anti-Tuberculosis Activity", Mar. Drugs 2021, 19, 446. DOI: 10.3390/md19080446.

251   M. Kohr, U. Kazmaier, "C–H Functionalization of Peptides via Cyclic Aminal Intermediates", Org. Lett. 2021, 23, 5947-5951. DOI: 10.1021/acs.orglett.1c02041.

250   O. Andler, U. Kazmaier, "Total Synthesis of Apratoxin A and B using Matteson's Homologation Approach", Org. Biomol. Chem. 2021, 19, 4866–4870. DOI: 10.1039/d1ob00713k.

249   L. Junk, E. Papadopoulos, U. Kazmaier, "Tryptophan N1-Alkylation: Quick and Simple Access to Diversely Substituted Tryptophans", Synthesis 2021, 53, 2503–2511. DOI: 10.1055/a-1404-5079.

248   S. Kappler, U. Kazmaier, "Synthesis of modified miuraenamides – the Ugi approach", Arkivoc 2021, IV, 280–296. DOI: 10.24820/ark.5550190.p011.186.

247   S. Kappler, A. Siebert, U. Kazmaier, "Synthesis of New Cyclopeptide Analogues of the Miuraenamides", Curr. Org. Synth. 2021, 18, 418–424. DOI: 10.2174/1570179418666210113161550.

246   O. Andler, U. Kazmaier, "A Straightforward Synthesis of Polyketides via Ester Dienolate Matteson Homologation", Chem. Eur. J. 2021, 27, 949–953. DOI: 10.1002/chem.202004650.

245   U. Kazmaier, "The Long, Long Way to Bottromycin", Isr. J. Chem. 2021, 61, 302–321. DOI: 10.1002/ijch.202000068.