Prof. Dr. Fabian Erdel
The Dynamics of Biological Systems group investigates how proteins and other macromolecules move within the cell nucleus, assemble into condensates, and thereby affect genome organization, the mechanical properties of the nucleus, and cell function as a whole. We combine high-resolution microscopy, single-molecule techniques, and computational modeling to visualize cellular processes in space and time.
Particular areas of interest include:
- Organization and dynamics of chromatin in the cell nucleus as a basis for cell type-specific genome interpretation
- Formation and function of membrane-less condensates through phase separation, and their dysregulation
Interplay between mechanical forces, chromatin structure, and gene regulation
- Homepage of the group
