Publications antibody sources and antibody validation

  • Baker M. 1,500 scientists lift the lid on reproducibility. 2016. Nature 533:454.
  • Begley CG and Ellis LM. 2012. Drug development: Raise standards for preclinical cancer research. Nature 483:531–533.
  • Berglund L, Björling E, Oksvold P, Fagerberg L, Asplund A, Szigyarto CA, Persson A, Ottosson J, Wernérus H, Nilsson P, Lundberg E, Sivertsson A, Navani S, Wester K, Kampf C, Hober S, Pontén F, Uhlén. 2008. A genecentric Human Protein Atlas for expression profiles based on antibodies. Mol Cell Proteomics 7:2019-2027.
  • Baker M. 2015. Reproducibility crisis: Blame it on the antibodies. Nature 521:274-6.
  • Bradbury A and Plückthun A. 2015. Reproducibility: Standardize antibodies used in research. Nature 518:27-9.
  • Bordeaux J, Welsh A, Agarwal S, Killiam E, Baquero M, Hanna J, Anagnostou V, Rimm D. 2010. Antibody validation. Biotechniques 48:197-209.

Weitere Publikationen

  • Hoppstädter J, Dembek A, Höring M, Liebisch G, Dahlem C, Sultan A, Wirth N, Al-Fityan S, Diesel B, Gasparoni G, Walter J, Helms V, Huwer H, Simon M, Schulz MH, Kiemer AK. 2021. Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumor-associated macrophages. EBioMedicine 72:103578

  • Valbuena Perez JV, Linnenberger R, Dembek A, Bruscoli S, Riccardi C, Schulz MH, Meyer MR, Kiemer AK, Hoppstädter J. 2020. Altered glucocorticoid metabolism represents a feature of macroph-aging. Aging Cell 19:e13156

  • Dahlem C, Siow WX, Lopatniuk M, Fai Tse WK, Kessler SM, Kirsch SH, Hoppstädter J, Vollmar, AM, Müller R, Luzhetskyy ABartel K, Kiemer AK. 2020. Thioholgamide A, a new anti-proliferative anti-tumor agent, modulates macrophage polarization and metabolism. Cancers 12:1288

  • Goes A, Lapuhs P, Kuhn T, Schulz E, Richter R, Panter F, Dahlem C, Koch M, Garcia R, Kiemer AK, Müller R, Fuhrmann G. 2020. Myxobacteria-derived outer membrane vesicles: potential applicability against intracellular infections. Cells 9:194

  • Kessler SM, Hoppstädter J, Hosseini K, Laggai S, Haybaeck J, Kiemer AK. 2019. Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation. J Hepatol 70:175-177

  • Hoppstädter J, Dembek A, Linnenberger R, Dahlem C, Barghash A, Fecher-Trost C, Fuhrmann G, Koch M, Kraegeloh A, Huwer H, Kiemer AK. 2019. Toll-like receptor 2 release by macrophages: an anti-inflammatory program induced by glucocorticoids and lipopolysaccharide. Front Immunol 10:1634

  • Hoppstädter J, Diesel B, Hachenthal N, Minet M, Leidinger P, Backes C, Grässer F, Meese E, Bruscoli S, Riccardi C, Huwer H, Kiemer AK. 2019. Amplified host defense by Toll-like receptor-mediated downregulation of the glucocorticoid-induced leucine zipper (GILZ) in macrophages. Front Immunol 9:3111

  • Kiefer R, Jurisic M, Dahlem C, Koch M, Schmitt MJ, Kiemer AK, Schneider M, Breinig F. 2019. Targeted delivery of functionalized PLGA nanoparticles to macrophages by complexation with the yeast Saccharomyces cerevisiae. Biotechnol Bioeng 117:776-788

  • Schultheiss CS, Laggei S, Czepukojc B, Hussein UK, List M, Barghash A, Tierling S, Hosseini K, Golob-Schwarzl N, Pokorny J, Hachenthal N, Schulz M, Helms V, Walter J, Zimmer V, Lammert F, Bohle RM, Dandolo L, Haybaeck J, Kiemer AK, Kessler SM. 2017. The long non-conding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma. Cell Stress 1:37-57

  • Seif M, Hoppstädter J, Breinig F, Kiemer AK. 2017. Yeast-mediated mRNA delivery polarizes immuno-suppressive macrophages towards an immuno-stimulatory phenotype. Eur J Pharm Biopharm 117:1-13

  • Hoppstädter J, Hachenthal N, Valbuena-Perez JV, Lampe S, Astanina K, Kunze MM, Bruscoli S, Riccardi C, Schmid T, Diesel B, Kiemer AK. 2016. Induction of glucocorticoid-induced leucine zipper (GILZ) contribut to anti-inflammatory effects of the natural product curcumin in macrophages. J Biol Chem 291(44): 22949-22960.