Abschlussarbeiten

Dissertationen

Lott D, Quantitative Assessment of the effects of the selective S1P1 receptor modulator ponesimod using pharmacometric modeling and simulation, 2018

Moj D, Translational physiologically-based pharmacokinetic (PBPK) modeling and simulation to support drug development and pharmacotherapy, 2018

Titze M, Novel approaches for translational research in oncology: Pharmacometric modeling of oncolytic virus dynamics and a new Tyrosine Kinase Inhibitor, 2017

 

Master / Diplom

Erhebung der Qualität des Entlassmanagements in der Inneren Medizin eines vollversorgenden Krankenhauses, 2019

Erhebung und Evaluation arzneimittelbezogener Probleme nach hämatopoetischer Stammzelltransplantation, 2019

Physiologically-based pharmacokinetic modelingof the DPYD substrate 5-fluorouracil and its prodrug capecitabine, 2019

Effective removal of dabigatran by idarucizumab - a physiologically-based pharmacokinetic modeling approach, 2019

Whole-body physiologically-based pharmacokinetic (PBPK) modeling of CYP3A4 inhibitors: Verapamil and its metabolite norverapamil, 2018

Medikationsanalyse bei hämatopoetischer Stammzelltransplantation, 2018

Der Bundeseinheitliche Medikationsplan in der Praxis - Statusanalyse anhand von stationär aufgenommenen Patienten im Klinikum Saarbrücken, 2018

Physiologically-based pharmacokinetic modeling of the CYP2C8 substrate pioglitazone, 2017

A population pharmacokinetic model of cortisol stress response, 2017

A mathematical semi-mechanistic cancer cell cycle model to predict effects of combination therapy and different dosing schedules on cell cycle, tumor growth and therapy outcome, 2016

A physiologically-based pharmacokinetic model of the strong CYP2C8 inhibitor gemfibrozil, 2016

Pharmacokinetic and pharmacodynamic modeling of acetylsalicylic acid and its major metabolites, 2016

Physiologically-based pharmacokinetic (PBPK) modeling of dronedarone, 2016

Impact of chronopharmacology on the pharmacokinetics-pharmacodynamics of propanolol - a mathematical approach, 2015

Population pharmacokinetic modeling of MDMA (methylendioxymetamphetamine) and its metabolites MDA and HMMA in Ecstasy users, 2014

Investigation of influencing factors on the pharmacokinetic and pharmacodynamic of mirtazapine, 2014