Welcome to the Center for Biophysics

The Center for Biophysics works on the theoretical and experimental modeling of non-equilibrium processes in biological systems and cells. The aim of this modeling is to uncover and understand the physical principles that arise from the interaction of many molecular and cellular actors and thus give rise to the many different forms and functions of living matter.

The Center is characterized by close interdisciplinary cooperation between medicine, biology, and physics. This enables not only the development of advanced theoretical models, but also their subsequent experimental validation.


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Ludger Santen elected as President of Saarland University

Ludger Santen, Professor forr Theoretical Physics (Saarland University) and director of the Center for Biophysics, has been elected to be become the President of Saarland University. His term will start on  April 1, 2024. Congratulations!

Press release of Saarland University from December 1, 2023 (in German).





Successful first-stage proposal on AI-empowered drug discovery and development
On February 2, the German Research Foundation (DFG) and the German Council of Science and Humanities (Wissenschaftsrat, WR) announced which initiatives for new Clusters of Excellence will be invited to submit full proposals. Saarland University (UdS) has successfully cleared this first hurdle with its proposal "nextAID³ - Next Generation of Cl-driven Drug Discovery and Development".
Press release of Saarland University (2.2.2024, in German)

Vesicles driven by dynein and kinesin exhibit directional reversals without regulators
Intracellular vesicular transport along cytoskeletal filaments ensures targeted cargo delivery. In a recent publication in Nature Communications, the Santen lab - together with the group of Stefan Diez (TU Dresden) - demonstrate that a minimal system, comprising purified Dynein-Dynactin-BICD2 (DDB) and kinesin-3 (KIF16B) attached to large unilamellar vesicles, faithfully reproduces in vivo cargo motility, including runs, pauses, and reversals.

Emmy-Noether-Group: Oskar Staufer 
Oskar Staufer secured a prestigious Emmy-Noether grant including funding of 2.4 Million Euro to boost his research on the analysis of biophysical adaptation mechanisms in the tumor-immune microenvironment using synthetic cell systems. Congratuations!
Press release of Saarland University of 10.11.2023 (in German)

Further News