Decision support

Models only help if their results reach the bedside or the pharmacy. We develop tools that support physicians, pharmacists and patients in therapy decisions: for dosing, for drug interactions and for estimating the risk of complications.

How we work

We combine pharmacometric models with clinical data and methods of artificial intelligence. One example is the Medication Management Center from the EU project SafePolyMed, another are models that predict complications after stem cell transplantation early on.

Selected publications

• Gepp SC, Schera F, Marok F, … Lehr T, Kiefer S. The SafePolyMed Medication Management Center: A patient-centered platform for improving safety in polypharmacy. Curr Dir Biomed Eng. 2026;12(1):163-166.
• Götz KM, Turki AT, Och K, … Lehr T. Model-based prediction of clinically relevant thrombocytopenia after allogeneic hematopoietic stem cell transplantation. Clin Pharmacol Ther. 2025;117(5):1413-1426.
• Götz KM, Kreuer S, Volz AK, … Lehr T. Population pharmacokinetics of intravenous fosfomycin: dose optimization for critically ill patients with and without kidney replacement therapy. Antimicrob Agents Chemother. 2025;69(6):e0177924.